ASD

GO:0051281 positive regulation of release of sequestered calcium ion into cytosol (13)

GeneInput weightStandardRank
SNCA--1667
DRD10.251899
THY1--1580
TRPC1--2648
LHCGR0.2513057
EDNRA--13857
LACRT--7733
XCL1--7819
F2RL3--9626
IL13--12888
BDKRB1--18217
F2--118599
F2R--20036

Network

GO:0051281

Network
Enrichment
NameDescriptionExternal IDs
SNCAsynuclein, alpha (non A4 component of amyloid precursor) Entrez:6622  HPRD: 01227  HGNC: 11138  Ensembl: ENSG00000145335 
DRD1dopamine receptor D1 Entrez:1812  HPRD: 00538  HGNC: 3020  Ensembl: ENSG00000184845 
THY1Thy-1 cell surface antigen Entrez:7070  HGNC: 11801  HPRD: 01769 
TRPC1transient receptor potential cation channel, subfamily C, member 1 Entrez:7220  HPRD: 11894  HGNC: 12333  Ensembl: ENSG00000144935 
LHCGRluteinizing hormone/choriogonadotropin receptor Entrez:3973  HGNC: 6585  Ensembl: ENSG00000138039  HPRD: 01073 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SNCAsynuclein, alpha (non A4 component of amyloid precursor)
DRD1dopamine receptor D1
THY1Thy-1 cell surface antigen
TRPC1transient receptor potential cation channel, subfamily C, member 1
LHCGRluteinizing hormone/choriogonadotropin receptor
Query geneGeneGene descriptionEdge score
SNCASNCAsynuclein, alpha (non A4 component of amyloid precursor)
DRD1DRD1dopamine receptor D1
THY1THY1Thy-1 cell surface antigen
TRPC1TRPC1transient receptor potential cation channel, subfamily C, member 1
LHCGRLHCGRluteinizing hormone/choriogonadotropin receptor

Troyanskaya Laboratory - Princeton University