ASD

GO:0033555 multicellular organismal response to stress (41)

GeneInput weightStandardRank
NEUROD2--98
GRM70.251137
GABRA50.251161
GRIK20.51232
CACNA1A--1270
MAPK8IP2--418
CRHR1--589
CACNA1B--593
RELN1.01626
TAC10.251726
GRIN2B1.01763
BDNF0.251791
NOS10.251853
DRD10.251899
NR2E10.251977
CALCA--1013
ADRB1--1057
PENK--1146
ADCYAP1R1--1273
ADRA2A0.2511399
RUNX1--11449
CCK0.2511899
TRPA1--2604
PRL0.2512977
GNG7--3815
TSPO0.2514009
KCNIP3--5600
LGALS1--6065
DRD40.2517021
TRPV10.2517162
DBH0.25110495
TACR1--11618
GCH10.25111867
HMGCS2--12061
COMT0.25113475
GJA4--14415
P2RX3--18725
OSM--19580
VDAC1--20059
MDK--22733
IDO1--23074

Network

GO:0033555

Network
Enrichment
NameDescriptionExternal IDs
NEUROD2neuronal differentiation 2 Entrez:4761  HPRD: 03429  HGNC: 7763 
GRM7glutamate receptor, metabotropic 7 Entrez:2917  HGNC: 4599  Ensembl: ENSG00000196277  HPRD: 04979 
GABRA5gamma-aminobutyric acid (GABA) A receptor, alpha 5 Entrez:2558  Ensembl: ENSG00000186297  HPRD: 08840  HGNC: 4079 
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  Ensembl: ENSG00000164418  HGNC: 4580  HPRD: 00692 
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit Entrez:773  HPRD: 03004  HGNC: 1388  Ensembl: ENSG00000141837 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NEUROD2neuronal differentiation 2
GRM7glutamate receptor, metabotropic 7
GABRA5gamma-aminobutyric acid (GABA) A receptor, alpha 5
GRIK2glutamate receptor, ionotropic, kainate 2
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
Query geneGeneGene descriptionEdge score
NEUROD2NEUROD2neuronal differentiation 2
GRM7GRM7glutamate receptor, metabotropic 7
GABRA5GABRA5gamma-aminobutyric acid (GABA) A receptor, alpha 5
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit

Troyanskaya Laboratory - Princeton University