ASD

GO:0030819 positive regulation of cAMP biosynthetic process (29)

GeneInput weightStandardRank
DRD10.251899
ADRB1--1057
DRD50.2511103
ADCYAP1R1--1273
AKAP5--1759
SPECC1L--1912
PTHLH--11993
MC2R--3795
AKAP12--3839
MC4R0.2513850
GSK3A--4141
GHRHR--4237
ABCA1--14703
MC5R--4977
GCG--5190
MRAP2--5265
RXFP2--15887
PTH--6947
GHRH--7478
MC1R--17999
MC3R0.2518188
ADORA2A0.2518408
GIPR--10369
MRAP--10905
AVP--113439
INSL3--119059
ADORA2B--19522
GPR65--22555
ADCY7--25408

Network

GO:0030819

Network
Enrichment
NameDescriptionExternal IDs
DRD1dopamine receptor D1 Entrez:1812  HPRD: 00538  HGNC: 3020  Ensembl: ENSG00000184845 
ADRB1adrenoceptor beta 1 Entrez:153  HGNC: 285  Ensembl: ENSG00000043591  HPRD: 00181 
DRD5dopamine receptor D5 Entrez:1816  HGNC: 3026  Ensembl: ENSG00000169676  HPRD: 00542 
ADCYAP1R1adenylate cyclase activating polypeptide 1 (pituitary) receptor type I Entrez:117  HGNC: 242  Ensembl: ENSG00000078549  HPRD: 00045 
AKAP5A kinase (PRKA) anchor protein 5 Entrez:9495  HGNC: 375  HPRD: 05255 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
DRD1dopamine receptor D1
ADRB1adrenoceptor beta 1
DRD5dopamine receptor D5
ADCYAP1R1adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
AKAP5A kinase (PRKA) anchor protein 5
Query geneGeneGene descriptionEdge score
DRD1DRD1dopamine receptor D1
ADRB1ADRB1adrenoceptor beta 1
DRD5DRD5dopamine receptor D5
ADCYAP1R1ADCYAP1R1adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
AKAP5AKAP5A kinase (PRKA) anchor protein 5

Troyanskaya Laboratory - Princeton University