ASD

GO:0042177 negative regulation of protein catabolic process (30)

GeneInput weightStandardRank
GRIN2A0.25166
SMAD4--821
SMAD3--823
FYN--932
RELA--1142
BAG6--1305
PRKCG--11483
N4BP1--1749
AGAP2--2378
USP44--3406
SERPINE2--3708
HSP90AB1--3924
FLNA--14285
FURIN--4605
PTPN3--4627
GRIN2C--5801
SERPINB12--7487
MDM4--7770
TIMP1--8520
IL10--19513
GIPC1--9877
TAF9--10627
NOS20.25111577
MAD2L2--13802
IRAK3--14633
SHH--118571
INS--122047
UBXN1--23735
TIMP3--23921
MAD2L1--25321

Network

GO:0042177

Network
Enrichment
NameDescriptionExternal IDs
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
SMAD4SMAD family member 4 Entrez:4089  Ensembl: ENSG00000141646  HGNC: 6770  HPRD: 02995 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
FYNFYN oncogene related to SRC, FGR, YES Entrez:2534  HGNC: 4037  Ensembl: ENSG00000010810  HPRD: 00655 
RELAv-rel avian reticuloendotheliosis viral oncogene homolog A Entrez:5970  HGNC: 9955  HPRD: 01241  Ensembl: ENSG00000173039 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
SMAD4SMAD family member 4
SMAD3SMAD family member 3
FYNFYN oncogene related to SRC, FGR, YES
RELAv-rel avian reticuloendotheliosis viral oncogene homolog A
Query geneGeneGene descriptionEdge score
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
SMAD4SMAD4SMAD family member 4
SMAD3SMAD3SMAD family member 3
FYNFYNFYN oncogene related to SRC, FGR, YES
RELARELAv-rel avian reticuloendotheliosis viral oncogene homolog A

Troyanskaya Laboratory - Princeton University