GO:0070498 interleukin-1-mediated signaling pathway (9)

GeneInput weightStandardRank
PLCB1--148
RPS6KA5--359
EGR1--3062
MAPK30.2516426
RPS6KA4--10148
IRAK3--14633
IRAK2--15024
IRAK1--21640
IL1R1--23779

Network

GO:0070498

Network
Enrichment
NameDescriptionExternal IDs
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5 Entrez:9252  Ensembl: ENSG00000100784  HPRD: 06789  HGNC: 10434 
EGR1early growth response 1 Entrez:1958  HGNC: 3238  HPRD: 00549  Ensembl: ENSG00000120738 
MAPK3mitogen-activated protein kinase 3 Entrez:5595  HGNC: 6877  Ensembl: ENSG00000102882  HPRD: 03479 
RPS6KA4ribosomal protein S6 kinase, 90kDa, polypeptide 4 Entrez:8986  HGNC: 10433  Ensembl: ENSG00000162302  HPRD: 04677 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5
EGR1early growth response 1
MAPK3mitogen-activated protein kinase 3
RPS6KA4ribosomal protein S6 kinase, 90kDa, polypeptide 4
Query geneGeneGene descriptionEdge score
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
RPS6KA5RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5
EGR1EGR1early growth response 1
MAPK3MAPK3mitogen-activated protein kinase 3
RPS6KA4RPS6KA4ribosomal protein S6 kinase, 90kDa, polypeptide 4