ASD

GO:0032410 negative regulation of transporter activity (22)

GeneInput weightStandardRank
CALM3--352
SNCA--1667
IL1RAPL10.251774
CALM1--1029
ADRA2A0.2511399
NCS1--2628
CALM2--2814
STIM2--3653
DRD20.2513749
DRD30.2514349
GNAI2--5860
INSR--15872
OPRD10.2516030
NDFIP1--6744
DRD40.2517021
NDFIP2--10157
RHOC--11655
WWP2--11885
APOA2--14659
EPO--20282
SLC9A3R1--21898
ADRB20.25123251

Network

GO:0032410

Network
Enrichment
NameDescriptionExternal IDs
CALM3calmodulin 3 (phosphorylase kinase, delta) Entrez:808  HPRD: 00243  Ensembl: ENSG00000160014  HGNC: 1449 
SNCAsynuclein, alpha (non A4 component of amyloid precursor) Entrez:6622  HPRD: 01227  HGNC: 11138  Ensembl: ENSG00000145335 
IL1RAPL1interleukin 1 receptor accessory protein-like 1 Entrez:11141  HPRD: 02193  HGNC: 5996 
CALM1calmodulin 1 (phosphorylase kinase, delta) Entrez:801  HPRD: 00241  HGNC: 1442  Ensembl: ENSG00000198668 
ADRA2Aadrenoceptor alpha 2A Entrez:150  HGNC: 281  HPRD: 00078  Ensembl: ENSG00000150594 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CALM3calmodulin 3 (phosphorylase kinase, delta)
SNCAsynuclein, alpha (non A4 component of amyloid precursor)
IL1RAPL1interleukin 1 receptor accessory protein-like 1
CALM1calmodulin 1 (phosphorylase kinase, delta)
ADRA2Aadrenoceptor alpha 2A
Query geneGeneGene descriptionEdge score
CALM3CALM3calmodulin 3 (phosphorylase kinase, delta)
SNCASNCAsynuclein, alpha (non A4 component of amyloid precursor)
IL1RAPL1IL1RAPL1interleukin 1 receptor accessory protein-like 1
CALM1CALM1calmodulin 1 (phosphorylase kinase, delta)
ADRA2AADRA2Aadrenoceptor alpha 2A

Troyanskaya Laboratory - Princeton University