ASD

GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter (96)

GeneInput weightStandardRank
ESRRG--122
RORB--283
RARB0.251300
NR3C1--496
NR1D2--526
PAX60.251544
THRA--614
CTBP1--760
THRB--1881
NR4A3--1963
NR2E10.251977
NR4A20.251992
MED1--1034
PRKCB0.511186
SIRT1--1233
RXRB0.2511314
UBE2I--1578
NR5A2--1591
RBPJ--1595
NR3C20.511624
CCNA1--1668
NR2F1--1728
NR2C2--1790
ESR10.2511791
AR0.2511902
NR1D1--1920
PKN1--1967
ESR20.2512114
NR0B1--12278
SREBF2--2312
DLX20.2512357
DLX10.2512400
PCNA--2671
SCAP--2683
SRF--2841
NOTCH1--12865
RXRG0.2512866
PGR--2926
NR1H4--3080
KDM4C--3226
RORA--3270
NR6A1--3495
RARA0.2513695
PIAS4--3989
PPARA--4177
RBM15--4247
ESRRB0.2514453
HNF4G--4499
NKX6-1--4665
NKX6-2--4791
NPAT--5362
NR1H2--6183
NRBP1--6253
PPARD--6562
RB1--16804
NR5A1--17328
E2F6--7333
NR2C1--7841
NKX2-50.2518486
RARG0.2518575
LBX1--9134
NR1I2--9659
DGKQ--9874
NR1I3--10378
GFI1--111098
KDM1A--12183
NR2E3--112274
RXRA0.25112299
NR4A1--12498
EVX1--15344
ARHGEF10L--17881
SREBF1--19464
HINFP--19490
NR2F6--20478
ESRRA--21277
NR0B2--121425
RORC--21698
VDR--21837
NRBF2--22616
PPARG--122729
HNF4A--122965
E2F1--23057
POLA1--23566
E2F4--24064
CCNE1--24359
NR2C2AP--24955
NR1H3--25006
CDK1--25053
TYMS--25226
CDT1--25291
FBXO5--25488
RRM2--25603
ORC1--25714
CDC45--25728
DHFR0.25125817
CDC6--25819

Network

GO:0010551

Network
Enrichment
NameDescriptionExternal IDs
ESRRGestrogen-related receptor gamma Entrez:2104  HGNC: 3474  Ensembl: ENSG00000196482  HPRD: 04274 
RORBRAR-related orphan receptor B Entrez:6096  HPRD: 09062  Ensembl: ENSG00000198963  HGNC: 10259 
RARBretinoic acid receptor, beta Entrez:5915  HPRD: 07183  Ensembl: ENSG00000077092  HGNC: 9865 
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Entrez:2908  HPRD: 00679  HGNC: 7978  Ensembl: ENSG00000113580 
NR1D2nuclear receptor subfamily 1, group D, member 2 Entrez:9975  HGNC: 7963  Ensembl: ENSG00000174738  HPRD: 03809 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ESRRGestrogen-related receptor gamma
RORBRAR-related orphan receptor B
RARBretinoic acid receptor, beta
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR1D2nuclear receptor subfamily 1, group D, member 2
Query geneGeneGene descriptionEdge score
ESRRGESRRGestrogen-related receptor gamma
RORBRORBRAR-related orphan receptor B
RARBRARBretinoic acid receptor, beta
NR3C1NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR1D2NR1D2nuclear receptor subfamily 1, group D, member 2

Troyanskaya Laboratory - Princeton University