ASD

GO:0006875 cellular metal ion homeostasis (271)

GeneInput weightStandardRank
ATP2B20.513
GNB1--24
HTR2C0.25162
HTR2A0.251121
KCNMA10.251191
PRKCE--204
GRIK20.51232
GNB2--258
CACNA1A--1270
ATP6V0B--277
GRIN1--294
SLC8A2--334
SV2A--354
ATP6V1G2--367
NEDD4L--495
ATP6V0C0.251502
ATP6V0D1--539
JPH3--580
CRHR1--589
TAC10.251726
KCNA5--1743
CCKBR--794
GPR6--796
CACNA1C--1807
ATP6V1A--886
DRD10.251899
GNG3--927
RYR2--1959
CALCA--1013
GPR12--1064
KCNK3--1065
HIF1A--1075
DRD50.2511103
NPY1R0.2511190
APP--1515
SLC8A1--1529
RYR30.2511563
PTGER3--1587
NR3C20.511624
ATP6V1B2--1815
CHRNA70.511837
ADRA1A--1858
TGFA--1873
STC1--1900
ATP6V0A1--2034
ATP1A2--12247
SLC24A2--2302
CUL5--2323
FKBP1B--2346
CALCR--2381
ATP6V1F--2424
SLC22A17--2572
TRPC1--2648
SOD1--12702
CHRNA9--2714
MCHR10.2512905
ATP7B--12928
TRPC60.512954
JPH1--3027
PTK2B--3063
MT3--3160
NPTN--3227
JPH4--3380
STIM2--3653
IL6ST--3678
DRD20.2513749
AVPR1A0.513803
EDNRA--13857
ITGB1--3903
CCR9--4018
ATP6V1E1--4070
SLC8A3--4131
LPAR1--4170
S1PR1--4301
P2RY1--4342
DRD30.2514349
TF--14527
ATP6V1G1--4576
PTH1R--4648
PROK2--14655
CCR8--4957
GCM2--5007
CALCB--5145
CCR3--5157
CCL1--5289
ATP6V1H--5369
CXCR4--5414
GNAT2--5443
CLDN16--5495
CHERP--5827
ATP6V1D--6195
CCR4--6209
ATP2C1--16243
OPRL10.2516271
AGTR1--16275
TFRC--6349
OXTR0.516388
ATP6V1G3--6391
NMUR2--6430
LPAR2--6450
XCR1--6470
PLN0.2516577
NDFIP1--6744
S1PR3--6774
KNG1--6802
HEPH--6867
PLCE1--6929
PTH--6947
HTR2B--6992
RXFP3--6996
DRD40.2517021
TRPV10.2517162
CASR--7200
SLC30A1--7241
P2RY4--7298
CDH23--17406
GHRH--7478
ATP6V0A4--7653
PYGM--17766
CXCL12--7802
XCL1--7819
IL2--7838
MTL5--7866
CD24--18102
CXCL13--8148
PDE6B--18154
ABCG2--8170
ATP6V1C2--8391
CCL13--8493
CYSLTR1--8518
AVPR1B0.2518546
TFR2--18706
SCARA5--8763
TMPRSS3--18916
ATP6V0D2--9130
GHRL0.2519242
RGN--9311
HPX--9337
SLC40A1--19418
EDN1--9540
CCL11--9615
GLP1R--9893
FTH1--9971
ATP6V0E2--10017
CHRNA10--10096
BDKRB2--10150
PDE6A--10187
GIPR--10369
CLN3--110442
ATP6V0A2--10497
ATP6V1B1--10564
IL1B--110818
CSRP3--110846
MFI2--11113
MICU1--11165
OXT0.25111176
PIK3CB--11542
CACNA1F0.25111612
TACR1--11618
HCRT0.25111633
CCKAR--11747
FTHL17--11798
CCL7--11841
LPAR3--11897
ATP6V1E2--12277
TTC7A--12351
FTL--12386
HERPUD1--12415
PMCH--12542
CP--112565
TNNI3--112758
SLC11A2--112770
WFS10.25112793
FGF2--13150
FTMT--13239
AGT--113305
AVP--113439
SLC46A1--13637
UTS2R--13768
RYR1--113799
CD55--14043
MCOLN1--114169
CCR6--14313
CCR10--14318
CCL19--14578
GDF2--14603
GALR2--14926
CCL23--15011
CAV3--115414
ELANE--115526
MT4--15819
FXYD1--15840
TRPV4--115988
FZD2--16930
RNR2--17244
CCR5--17585
HP--17916
BDKRB1--18217
PSEN1--18523
FTH1P19--18576
F2--118599
CCL3--18656
EDN2--18677
JPH2--18890
CCL15--19406
TBXA2R--19479
CCL28--19780
F2RL1--19969
F2R--20036
TGFB10.25120135
JAK3--20340
BBC3--20534
ALAS2--120776
GNA15--20926
SRI--21103
ADM--21106
C5AR1--21363
CXCR3--21424
HSP90B1--21432
CD380.25121442
PTPRC--21546
LTF--21622
ATP6V1C1--21645
ITPR3--21697
MON1A--21794
CCL21--21829
VDR--21837
CCR1--21851
C5--122004
S1PR4--22105
CALR--22152
ATP2A1--122234
HMOX2--22285
HAMP--122361
CCR7--22367
SAA1--22464
MYC--122615
IBTK--22790
CD52--22795
MCU--22796
TGM2--23204
TCIRG1--123264
CCR2--23296
EPHX2--23371
APOE0.25123516
TPCN2--23548
SLC11A1--23561
C3AR1--23652
CCL14--23698
HMOX1--23938
FLVCR1--24042
P2RY2--24088
SAA2--24171
ABCB6--24248
EPOR--24273
ANXA7--24475
HFE0.25124705
PLCG2--24731
LCK--24753
NUBP1--24876
STEAP3--24919
ABCB7--125160
LCN2--25233
CYBRD1--25244
PML--25277
TPT1--25343
CAV1--125381
ACO1--25454
HEXB--125497
ATP6V0E1--25547
FXN--125604

Network

GO:0006875

Network
Enrichment
NameDescriptionExternal IDs
ATP2B2ATPase, Ca++ transporting, plasma membrane 2 Entrez:491  HGNC: 815  Ensembl: ENSG00000157087  HPRD: 00160 
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1 Entrez:2782  HGNC: 4396  HPRD: 00766  Ensembl: ENSG00000078369 
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Entrez:3358  HGNC: 5295  HPRD: 02429  Ensembl: ENSG00000147246 
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Entrez:3356  HPRD: 01638  Ensembl: ENSG00000102468  HGNC: 5293 
KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1 Entrez:3778  Ensembl: ENSG00000156113  HGNC: 6284  HPRD: 15967 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ATP2B2ATPase, Ca++ transporting, plasma membrane 2
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1
Query geneGeneGene descriptionEdge score
ATP2B2ATP2B2ATPase, Ca++ transporting, plasma membrane 2
GNB1GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
HTR2CHTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR2AHTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
KCNMA1KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1

Troyanskaya Laboratory - Princeton University