ASD

GO:0010243 response to organic nitrogen (118)

GeneInput weightStandardRank
GNAO1--4
PLCB1--148
GRIN2A0.25166
SLC1A2--119
PIK3R10.251150
PPP3CA--244
GRIN1--294
SLC6A10.251313
APLP1--591
GRIN2B1.01763
HPRT1--1842
DRD10.251899
NR4A20.251992
DRD50.2511103
SST--1139
RELA--1142
GNAL--1177
RPS6KB1--1521
DCC--1687
PPP3CB--1731
CDO1--1847
SMAD1--1872
SPECC1L--1912
SIN3A--2391
PDE1B--2534
DPYSL2--2672
SOD1--12702
BTG2--3036
PTK2B--3063
PPP1R1B0.2513111
ALDOB--3137
MAX--3376
DRD20.2513749
PRKAA2--3894
UBR2--4054
ALDOC--4093
DRD30.2514349
IL1A--4651
RRAGA--4695
PLCG1--4744
TH0.2514933
ADRA1B0.2514946
SRD5A10.2514966
PTGS20.2515085
ATP4B--5216
UBR1--15553
MSH2--16311
GIP--6352
OXTR0.516388
SLC18A2--6423
BCL2L1--6563
RRAGB--6607
DRD40.2517021
PRTFDC1--7244
CYBA--17322
RRAGC--7372
UROS--17645
GPRC6A--7662
CDKN1A--7714
HMGCS1--7719
CCND1--17970
ADORA2A0.2518408
GSTP10.2518742
LAMTOR2--8770
ARG2--8780
RRAGD--9082
AACS--9143
PIK3C3--9358
EDN1--9540
ASNS--9796
LYN--10336
DBH0.25110495
IL1B--110818
OXT0.25111176
CNR20.25111649
RHOC--11655
PSMB2--11986
HMGCS2--12061
TRDMT1--12254
IL6--112695
CPS1--112820
MMP3--13496
ND5--14164
RPTOR--14284
DDIT3--14883
PEBP1--15772
CASP12--18416
SHH--118571
TP73--18810
ARG1--119499
NOS3--20542
LAMTOR3--20937
MTOR--21095
HNMT--21489
LAMTOR1--22090
PEMT--22436
PLA2G4A--22727
AARS--22782
CROT--22812
TNFRSF1A--22842
CASP6--23087
MGST1--23219
GSS--23506
CCNG1--23565
CTGF--23607
ICAM1--23720
FDX1--23764
TIMP3--23921
ASS1--124321
CCNE1--24359
UROD--124523
PTGS1--24613
CAD--24868
CDK1--25053
IL1RN0.25125385
MGST2--25529
CTSB--25627
NNMT--25643

Network

GO:0010243

Network
Enrichment
NameDescriptionExternal IDs
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Entrez:2775  HPRD: 00757  HGNC: 4389  Ensembl: ENSG00000087258 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 2 Entrez:6506  Ensembl: ENSG00000110436  HGNC: 10940  HPRD: 02625 
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 2
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Query geneGeneGene descriptionEdge score
GNAO1GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
SLC1A2SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 2
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Troyanskaya Laboratory - Princeton University