ASD

GO:0032236 positive regulation of calcium ion transport via store-operated calcium channel activity (8)

GeneInput weightStandardRank
TRPC60.512954
HOMER10.2513402
STIM2--3653
PLCG1--4744
EFCAB4B--7947
STIM1--17385
ZP3--17443
PLCG2--24731

Network

GO:0032236

Network
Enrichment
NameDescriptionExternal IDs
TRPC6transient receptor potential cation channel, subfamily C, member 6 Entrez:7225  Ensembl: ENSG00000137672  HPRD: 04710  HGNC: 12338 
HOMER1homer homolog 1 (Drosophila) Entrez:9456  HPRD: 09211  HGNC: 17512 
STIM2stromal interaction molecule 2 Entrez:57620  Ensembl: ENSG00000109689  HGNC: 19205  HPRD: 11609 
PLCG1phospholipase C, gamma 1 Entrez:5335  Ensembl: ENSG00000124181  HPRD: 01398  HGNC: 9065 
EFCAB4BEF-hand calcium binding domain 4B Entrez:84766  HGNC: 28657  HPRD: 10079  Ensembl: ENSG00000130038 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
TRPC6transient receptor potential cation channel, subfamily C, member 6
HOMER1homer homolog 1 (Drosophila)
STIM2stromal interaction molecule 2
PLCG1phospholipase C, gamma 1
EFCAB4BEF-hand calcium binding domain 4B
Query geneGeneGene descriptionEdge score
TRPC6TRPC6transient receptor potential cation channel, subfamily C, member 6
HOMER1HOMER1homer homolog 1 (Drosophila)
STIM2STIM2stromal interaction molecule 2
PLCG1PLCG1phospholipase C, gamma 1
EFCAB4BEFCAB4BEF-hand calcium binding domain 4B

Troyanskaya Laboratory - Princeton University