ASD

GO:2000378 negative regulation of reactive oxygen species metabolic process (9)

GeneInput weightStandardRank
MYCN--560
PAX2--653
TFAP2A--12923
PRDX2--5497
HDAC6--16779
HP--17916
AATF--23243
CRYAB--124965
ACP5--25019

Network

GO:2000378

Network
Enrichment
NameDescriptionExternal IDs
MYCNv-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog Entrez:4613  Ensembl: ENSG00000134323  HGNC: 7559  HPRD: 01278 
PAX2paired box 2 Entrez:5076  HGNC: 8616  Ensembl: ENSG00000075891  HPRD: 01330 
TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha) Entrez:7020  Ensembl: ENSG00000137203  HGNC: 11742  HPRD: 00128 
PRDX2peroxiredoxin 2 Entrez:7001  HGNC: 9353  Ensembl: ENSG00000167815  HPRD: 02763 
HDAC6histone deacetylase 6 Entrez:10013  HGNC: 14064  Ensembl: ENSG00000094631  HPRD: 02228 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MYCNv-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
PAX2paired box 2
TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
PRDX2peroxiredoxin 2
HDAC6histone deacetylase 6
Query geneGeneGene descriptionEdge score
MYCNMYCNv-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
PAX2PAX2paired box 2
TFAP2ATFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
PRDX2PRDX2peroxiredoxin 2
HDAC6HDAC6histone deacetylase 6

Troyanskaya Laboratory - Princeton University