ASD

GO:0009755 hormone-mediated signaling pathway (31)

GeneInput weightStandardRank
NR3C1--496
THRA--614
NR4A3--1963
NR2E10.251977
BMP7--1137
NR3C20.511624
ESR10.2511791
NR1D1--1920
KDM3A--2069
ESR20.2512114
GHSR0.2512467
LATS1--2781
PGR--2926
LHCGR0.2513057
TRH--3416
PPARA--4177
ADIPOR2--5160
ASIP--5655
CUZD1--6357
BMP4--16499
PPARD--6562
GCGR--16828
NR2C1--7841
AGRP0.2518636
NUP62--18755
GHRL0.2519242
LATS2--9736
GHR--110098
NR2F6--20478
ADIPOR1--22393
PGRMC2--23461

Network

GO:0009755

Network
Enrichment
NameDescriptionExternal IDs
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Entrez:2908  HPRD: 00679  HGNC: 7978  Ensembl: ENSG00000113580 
THRAthyroid hormone receptor, alpha Entrez:7067  HGNC: 11796  Ensembl: ENSG00000126351  HPRD: 07185 
NR4A3nuclear receptor subfamily 4, group A, member 3 Entrez:8013  Ensembl: ENSG00000119508  HGNC: 7982  HPRD: 02766 
NR2E1nuclear receptor subfamily 2, group E, member 1 Entrez:7101  Ensembl: ENSG00000112333  HGNC: 7973  HPRD: 07230 
BMP7bone morphogenetic protein 7 Entrez:655  Ensembl: ENSG00000101144  HGNC: 1074  HPRD: 00212 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
THRAthyroid hormone receptor, alpha
NR4A3nuclear receptor subfamily 4, group A, member 3
NR2E1nuclear receptor subfamily 2, group E, member 1
BMP7bone morphogenetic protein 7
Query geneGeneGene descriptionEdge score
NR3C1NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
THRATHRAthyroid hormone receptor, alpha
NR4A3NR4A3nuclear receptor subfamily 4, group A, member 3
NR2E1NR2E1nuclear receptor subfamily 2, group E, member 1
BMP7BMP7bone morphogenetic protein 7

Troyanskaya Laboratory - Princeton University