ASD

GO:0090200 positive regulation of release of cytochrome c from mitochondria (11)

GeneInput weightStandardRank
HRK--1660
MLLT11--1960
BCL2L11--3469
BMF--6376
BNIP3--6953
PMAIP1--7385
PINK1--118609
BBC3--20534
BIK--20799
BAK1--21229
BID--22640

Network

GO:0090200

Network
Enrichment
NameDescriptionExternal IDs
HRKharakiri, BCL2 interacting protein (contains only BH3 domain) Entrez:8739  HGNC: 5185  HPRD: 04581 
MLLT11myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 Entrez:10962  HGNC: 16997  HPRD: 05251 
BCL2L11BCL2-like 11 (apoptosis facilitator) Entrez:10018  Ensembl: ENSG00000153094  HPRD: 04828  HGNC: 994 
BMFBcl2 modifying factor Entrez:90427  HPRD: 05881  HGNC: 24132  Ensembl: ENSG00000104081 
BNIP3BCL2/adenovirus E1B 19kDa interacting protein 3 Entrez:664  HGNC: 1084  HPRD: 04482 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
HRKharakiri, BCL2 interacting protein (contains only BH3 domain)
MLLT11myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
BCL2L11BCL2-like 11 (apoptosis facilitator)
BMFBcl2 modifying factor
BNIP3BCL2/adenovirus E1B 19kDa interacting protein 3
Query geneGeneGene descriptionEdge score
HRKHRKharakiri, BCL2 interacting protein (contains only BH3 domain)
MLLT11MLLT11myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
BCL2L11BCL2L11BCL2-like 11 (apoptosis facilitator)
BMFBMFBcl2 modifying factor
BNIP3BNIP3BCL2/adenovirus E1B 19kDa interacting protein 3

Troyanskaya Laboratory - Princeton University