ASD

GO:0042493 response to drug (340)

GeneInput weightStandardRank
GNAO1--4
HTR2C0.25162
GRIN2A0.25166
GAD20.25183
ERBB40.25186
CREB1--100
GAD10.251114
SLC1A2--119
HTR2A0.251121
NEUROD1--1127
SLC12A5--141
PIK3R10.251150
APC0.251266
YWHAZ0.251269
TOP1--308
EP300--1318
SFRP1--387
MAP1B--403
ABCC8--1406
ADCY10.251466
JUN--511
VLDLR0.251574
SNCA--1667
BDNF0.251791
NOS10.251853
PCSK1--898
DRD10.251899
PAPD7--900
FYN--932
LRP20.251984
ACACA--1017
KCNK3--1065
XPO1--1095
SST--1139
RELA--1142
ATP1A3--1236
PDE4A--1260
CHRNA3--1266
ADCYAP1R1--1273
GABRG30.2511299
ERBB3--1350
RPS6KB1--1521
SLC8A1--1529
JUNB--1547
CA4--11582
FOS--1680
ABCA2--1681
GNAS--11842
ADRA1A--1858
SMAD1--1872
TGFA--1873
SPECC1L--1912
SCN11A--1927
DVL3--2090
ENO2--2103
USP47--2202
ABCA3--2215
SREBF2--2312
DUSP6--2466
BCL20.2512485
TRPA1--2604
EMX1--2613
DPYSL2--2672
WFDC1--2701
SOD1--12702
ABCB10.2512753
CYP2A6--12792
BCHE--2809
ADD3--2861
VAV3--2908
CFTR--12951
PRL0.2512977
LHCGR0.2513057
PTK2B--3063
CYP2C8--3090
ALDOB--3137
SLC17A3--3238
TGIF1--13264
PARK7--13322
SRP72--3401
SRP19--3492
HCN2--3542
PDE3A--3628
CYP2C9--3660
NME2--3712
PDGFA--3731
DRD20.2513749
LCT--3753
CYP19A10.2513823
ITGB1--3903
SLC6A11--3917
CYP17A10.2513984
MFSD10--3986
TSPO0.2514009
UBE2B--4057
SLC6A40.2514137
FABP30.2514154
MAT2A--4189
MAS1--4244
ABAT0.2514348
DRD30.2514349
OTC--14449
GRK5--4595
NKX6-1--4665
INPPL1--4681
PTPRM--4769
CYP2C19--4815
TERF1--4825
SLC15A2--4920
TH0.2514933
SRD5A10.2514966
LPL--14975
CYP1A10.2515067
PTGS20.2515085
CYP7B1--15098
POR0.2515184
SFRP2--5252
ADAM17--5323
CYP2B6--5346
PDZK1--5810
OXCT1--5813
CST3--15894
ATP1A10.2515927
DDC0.2515929
ADIPOQ0.2516032
LGALS1--6065
CYP1A2--6074
SERPINA7--6130
PGF--6172
NGF0.2516229
MSH2--16311
MAOB0.2516329
GIP--6352
OXTR0.516388
TCF3--6420
SLC18A2--6423
IL4--6852
HTR2B--6992
REN--17086
CYBA--17322
NPPB--7334
SLC1A30.2517455
CPB2--7613
FOSL1--7629
SLC6A30.517659
CDKN1A--7714
HMGCS1--7719
SLC9A1--7776
CCND1--17970
MET1.018002
CYP11A10.2518063
HTR1B0.2518092
ABCG2--8170
RAB6C--8214
ABCC6--18218
RPH3AL--8235
NFATC2--8295
ADORA2A0.2518408
STAT3--18538
SEMA3C--8577
ATP4A--8774
ARG2--8780
CTNNB10.519066
AACS--9143
KCNJ11--19151
NPPC--9349
IL10--19513
EDN1--9540
LIPE--9564
SOCS1--9583
NR1I2--9659
REST--9779
PMS2--9823
HSD11B2--9892
CSAG2--9910
CYP3A4--9925
TXNIP--10069
BDKRB2--10150
LYN--10336
TGFBR2--110407
MAP2K6--10478
CSAG3--10576
AMH--10601
CHAT--10603
IL1B--110818
GATA6--110828
ATG5--11069
DAD1--11136
BLMH--11539
RHOC--11655
SMTNL1--11942
HMGCS2--12061
ABCD3--12290
APOBEC1--12314
GATA4--112466
ACTC1--112547
MVD--12555
CD69--12661
IL6--112695
CPS1--112820
IFNG--112827
VEGFC--12850
NAT8--12874
AIM2--13450
COMT0.25113475
NME1--113556
GRK1--113627
UTS2R--13768
APOC2--13818
GAL--13897
SLC22A12--13899
ABCG5--14086
QDPR0.25114344
NES--14479
GNA12--14481
APOA2--14659
DNMT3B--14663
BLOC1S3--14755
DDIT3--14883
BAG1--14923
IGFBP2--15026
TNF0.25115243
EBP--15294
PEBP1--15772
NBN--116066
AQP7P3--17015
UQCRFS1P1--17431
LTA--18082
TP530.25118277
CASP12--18416
ND1--18434
SS18--18696
SRP54--18826
MMP7--19190
SLC22A1--19237
SREBF1--19464
TBXA2R--19479
ARG1--119499
MVP--19651
ABCB4--119716
NDUFA10--120064
TIMP4--20100
RPP21--20122
TGFB10.25120135
IKBKB--20225
CAPN3--120523
NOS3--20542
FZD1--20775
PMS2CL--20781
SRR--20837
BGLAP--20875
ABCC1--21066
PDGFB--21071
BAK1--21229
XBP1--21326
TNFRSF11B--21340
COQ7--21416
CD380.25121442
HDAC3--21702
GK--21720
ALDH1A3--21739
AQP7--22006
CALR--22152
B2M--22154
XRCC1--22160
BCAR3--22344
IGF20.25122401
AQP1--22433
PEMT--22436
TXN2--22459
UGT1A1--122467
TLR3--22478
SLC22A5--122584
MYC--122615
SOCS3--22661
SOD2--22687
PPARG--122729
ANXA10.5122810
CROT--22812
SRP68--22956
HNF4A--122965
NCF2--122977
UQCRFS1--22993
CCL5--23042
ERBB2--123130
XPC--123150
MGST1--23219
PPOX--123262
BDH1--23265
ALDH3A10.25123281
LTC4S--23432
GGH--23462
LOX--23483
HADHA--23496
CARD9--123577
CDH1--123589
SRP14--23614
ICAM1--23720
NCKAP1L--23771
PRSS8--23956
CPT1A--23997
MGMT--24063
EI24--24294
ASS1--124321
CCNE1--24359
ENO3--24365
MMP9--24369
THBS1--24444
SLC22A18--124482
ACADM--24580
SLC19A10.25124631
FAS--124697
PARP4--24718
LCK--24753
TOP2A--24765
GCLM--24915
RAD54B--24958
ACSL1--24993
CDK1--25053
COL18A1--25059
NME1-NME2--25082
PAM--25108
SMPD1--125116
PLIN2--25164
CCNB1--25174
TYMS--25226
LCN2--25233
GPX3--25279
HADH--125329
CAV1--125381
GNPAT--125382
IL1RN0.25125385
CDK4--25490
CENPF--25495
MLH1--125513
PNP--125548
FXN--125604
NNMT--25643
RAD54L--125668
CTPS1--25804

Network

GO:0042493

Network
Enrichment
NameDescriptionExternal IDs
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Entrez:2775  HPRD: 00757  HGNC: 4389  Ensembl: ENSG00000087258 
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Entrez:3358  HGNC: 5295  HPRD: 02429  Ensembl: ENSG00000147246 
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) Entrez:2572  HPRD: 11817  HGNC: 4093  Ensembl: ENSG00000136750 
ERBB4v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 Entrez:2066  HGNC: 3432  HPRD: 02767  Ensembl: ENSG00000178568 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
ERBB4v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
Query geneGeneGene descriptionEdge score
GNAO1GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
HTR2CHTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
GAD2GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
ERBB4ERBB4v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Troyanskaya Laboratory - Princeton University