ASD

GO:0043154 negative regulation of caspase activity (45)

GeneInput weightStandardRank
DNAJB6--222
GPI--1423
PAX2--653
SNCA--1667
RPS6KA3--758
LEF1--1499
SPECC1L--1912
USP47--2202
SMAD6--2305
CDKN2D--2582
AKT2--13912
LAMTOR5--3937
TNFAIP3--4469
POR0.2515184
SFRP2--5252
XIAP--7332
NAIP--7984
ADORA2A0.2518408
CRYAA--10509
RAG1--10790
GPX10.25111644
HERPUD1--12415
NR4A1--12498
IL6--112695
SERPINB9--13041
PRDX5--13262
WNT9A--13365
AVP--113439
HSPA5--19143
CFLAR--19385
PRDX3--20199
DHCR24--21358
VIL10.5122243
TNFSF14--22260
IFI6--22523
CD27--22836
RPS6KA1--23184
THBS1--24444
TRIAP1--24476
CRYAB--124965
TNFAIP8--25001
IGBP1--25127
SFN--25459
DNAJA3--25610
BIRC5--25721

Network

GO:0043154

Network
Enrichment
NameDescriptionExternal IDs
DNAJB6DnaJ (Hsp40) homolog, subfamily B, member 6 Entrez:10049  HGNC: 14888  Ensembl: ENSG00000105993  HPRD: 07107 
GPIglucose-6-phosphate isomerase Entrez:2821  HPRD: 01394  HGNC: 4458  Ensembl: ENSG00000105220 
PAX2paired box 2 Entrez:5076  HGNC: 8616  Ensembl: ENSG00000075891  HPRD: 01330 
SNCAsynuclein, alpha (non A4 component of amyloid precursor) Entrez:6622  HPRD: 01227  HGNC: 11138  Ensembl: ENSG00000145335 
RPS6KA3ribosomal protein S6 kinase, 90kDa, polypeptide 3 Entrez:6197  HGNC: 10432  HPRD: 02092  Ensembl: ENSG00000177189 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
DNAJB6DnaJ (Hsp40) homolog, subfamily B, member 6
GPIglucose-6-phosphate isomerase
PAX2paired box 2
SNCAsynuclein, alpha (non A4 component of amyloid precursor)
RPS6KA3ribosomal protein S6 kinase, 90kDa, polypeptide 3
Query geneGeneGene descriptionEdge score
DNAJB6DNAJB6DnaJ (Hsp40) homolog, subfamily B, member 6
GPIGPIglucose-6-phosphate isomerase
PAX2PAX2paired box 2
SNCASNCAsynuclein, alpha (non A4 component of amyloid precursor)
RPS6KA3RPS6KA3ribosomal protein S6 kinase, 90kDa, polypeptide 3

Troyanskaya Laboratory - Princeton University