ASD

GO:0048663 neuron fate commitment (45)

GeneInput weightStandardRank
NTRK30.2516
ASCL1--413
POU4F1--475
PAX60.251544
OLIG2--619
SMAD4--821
NKX2-2--1120
CDC42--1138
JAG2--1612
ISL1--1974
FOXA1--1990
ID2--2154
DLX20.2512357
DLX10.2512400
FOXA2--2645
NOTCH1--12865
GSX1--3159
LHX6--3241
WNT8B--3407
PAX7--13577
NKX2-1--4142
WNT1--4383
AXIN1--14419
HOXD10--4534
NKX6-1--4665
NKX6-2--4791
HES5--4919
HOXC10--5156
PTF1A--5721
MNX1--5812
HES10.2515912
GLI3--16261
TLX3--6462
BMP4--16499
IHH--17160
TGFBR1--17268
GLI2--17307
GSX2--8581
LBX1--9134
FOXA3--10333
SMO0.25110504
ATOH1--11336
EVX1--15344
SHH--118571
NOTCH3--22114

Network

GO:0048663

Network
Enrichment
NameDescriptionExternal IDs
NTRK3neurotrophic tyrosine kinase, receptor, type 3 Entrez:4916  Ensembl: ENSG00000140538  HPRD: 01870  HGNC: 8033 
ASCL1achaete-scute complex homolog 1 (Drosophila) Entrez:429  HPRD: 00011  Ensembl: ENSG00000139352  HGNC: 738 
POU4F1POU class 4 homeobox 1 Entrez:5457  Ensembl: ENSG00000152192  HGNC: 9218  HPRD: 03379 
PAX6paired box 6 Entrez:5080  HPRD: 06167  Ensembl: ENSG00000007372  HGNC: 8620 
OLIG2oligodendrocyte lineage transcription factor 2 Entrez:10215  HPRD: 07334  Ensembl: ENSG00000205927  HGNC: 9398 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NTRK3neurotrophic tyrosine kinase, receptor, type 3
ASCL1achaete-scute complex homolog 1 (Drosophila)
POU4F1POU class 4 homeobox 1
PAX6paired box 6
OLIG2oligodendrocyte lineage transcription factor 2
Query geneGeneGene descriptionEdge score
NTRK3NTRK3neurotrophic tyrosine kinase, receptor, type 3
ASCL1ASCL1achaete-scute complex homolog 1 (Drosophila)
POU4F1POU4F1POU class 4 homeobox 1
PAX6PAX6paired box 6
OLIG2OLIG2oligodendrocyte lineage transcription factor 2

Troyanskaya Laboratory - Princeton University