ASD

GO:0045956 positive regulation of calcium ion-dependent exocytosis (9)

GeneInput weightStandardRank
PLCB1--148
CADPS--133
SCAMP50.2512682
GLRA1--2965
CDK50.2513194
CACNA1H1.013855
DOC2B--11084
ZP4--14747
ZP3--17443

Network

GO:0045956

Network
Enrichment
NameDescriptionExternal IDs
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
CADPSCa++-dependent secretion activator Entrez:8618  Ensembl: ENSG00000163618  HGNC: 1426  HPRD: 05236 
SCAMP5secretory carrier membrane protein 5 Entrez:192683  HGNC: 30386  HPRD: 18020  Ensembl: ENSG00000198794 
GLRA1glycine receptor, alpha 1 Entrez:2741  Ensembl: ENSG00000145888  HPRD: 00719  HGNC: 4326 
CDK5cyclin-dependent kinase 5 Entrez:1020  HGNC: 1774  HPRD: 00449 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CADPSCa++-dependent secretion activator
SCAMP5secretory carrier membrane protein 5
GLRA1glycine receptor, alpha 1
CDK5cyclin-dependent kinase 5
Query geneGeneGene descriptionEdge score
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CADPSCADPSCa++-dependent secretion activator
SCAMP5SCAMP5secretory carrier membrane protein 5
GLRA1GLRA1glycine receptor, alpha 1
CDK5CDK5cyclin-dependent kinase 5

Troyanskaya Laboratory - Princeton University