ASD

GO:0014074 response to purine-containing compound (17)

GeneInput weightStandardRank
SLC6A10.251313
RYR2--1959
GNAL--1177
SPECC1L--1912
BCL20.2512485
PRKAA2--3894
HMGCS1--7719
ADORA2A0.2518408
AACS--9143
IL6--112695
RYR1--113799
SDC20.25113950
PPARG--122729
P2RY2--24088
CCNE1--24359
CAD--24868
CHEK1--25816

Network

GO:0014074

Network
Enrichment
NameDescriptionExternal IDs
SLC6A1solute carrier family 6 (neurotransmitter transporter), member 1 Entrez:6529  Ensembl: ENSG00000157103  HGNC: 11042  HPRD: 00664 
RYR2ryanodine receptor 2 (cardiac) Entrez:6262  Ensembl: ENSG00000198626  HGNC: 10484  HPRD: 01619 
GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type Entrez:2774  HGNC: 4388  Ensembl: ENSG00000141404  HPRD: 00758 
SPECC1Lsperm antigen with calponin homology and coiled-coil domains 1-like Entrez:23384  HPRD: 11080  HGNC: 29022  Ensembl: ENSG00000100014 
BCL2B-cell CLL/lymphoma 2 Entrez:596  HGNC: 990  HPRD: 01045  Ensembl: ENSG00000171791 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SLC6A1solute carrier family 6 (neurotransmitter transporter), member 1
RYR2ryanodine receptor 2 (cardiac)
GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
SPECC1Lsperm antigen with calponin homology and coiled-coil domains 1-like
BCL2B-cell CLL/lymphoma 2
Query geneGeneGene descriptionEdge score
SLC6A1SLC6A1solute carrier family 6 (neurotransmitter transporter), member 1
RYR2RYR2ryanodine receptor 2 (cardiac)
GNALGNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
SPECC1LSPECC1Lsperm antigen with calponin homology and coiled-coil domains 1-like
BCL2BCL2B-cell CLL/lymphoma 2

Troyanskaya Laboratory - Princeton University