ASD

GO:0031111 negative regulation of microtubule polymerization or depolymerization (23)

GeneInput weightStandardRank
MAPT0.25176
MAP2--106
APC0.251266
MAPRE1--331
STMN2--343
CLASP2--375
MAP1B--403
SNCA--1667
CLIP3--730
CLASP1--955
ARHGEF2--1819
INPP5J--3690
TBCD--5702
KATNB1--8593
MID1IP1--9080
STMN1--9278
TRIM54--13879
HDAC6--16779
MAP4--20072
MAP6D1--20928
SBDS--21769
FKBP4--23829
CCNB1--25174

Network

GO:0031111

Network
Enrichment
NameDescriptionExternal IDs
MAPTmicrotubule-associated protein tau Entrez:4137  HGNC: 6893  Ensembl: ENSG00000186868  HPRD: 01142 
MAP2microtubule-associated protein 2 Entrez:4133  HPRD: 01140  HGNC: 6839  Ensembl: ENSG00000078018 
APCadenomatous polyposis coli Entrez:324  HGNC: 583  HPRD: 01439  Ensembl: ENSG00000134982 
MAPRE1microtubule-associated protein, RP/EB family, member 1 Entrez:22919  HGNC: 6890  HPRD: 04379  Ensembl: ENSG00000101367 
STMN2stathmin-like 2 Entrez:11075  HGNC: 10577  HPRD: 09003  Ensembl: ENSG00000104435 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MAPTmicrotubule-associated protein tau
MAP2microtubule-associated protein 2
APCadenomatous polyposis coli
MAPRE1microtubule-associated protein, RP/EB family, member 1
STMN2stathmin-like 2
Query geneGeneGene descriptionEdge score
MAPTMAPTmicrotubule-associated protein tau
MAP2MAP2microtubule-associated protein 2
APCAPCadenomatous polyposis coli
MAPRE1MAPRE1microtubule-associated protein, RP/EB family, member 1
STMN2STMN2stathmin-like 2

Troyanskaya Laboratory - Princeton University