ASD

GO:0048259 regulation of receptor-mediated endocytosis (31)

GeneInput weightStandardRank
SYNJ1--156
SH3GL2--454
BICD1--552
HNRNPK--885
CBL--1478
RAC1--1617
SGIP1--1665
HIP1--1797
PICALM--12597
ARF6--3317
DRD20.2513749
ANGPT1--4182
WNT3A--4747
SCYL2--7130
RSPO1--7229
SFRP4--7310
PCSK9--10760
DKK1--11567
MTMR2--113176
VTN--13271
APOC2--13818
APOA5--113831
PPT1--113834
CCL19--14578
SELE--14642
APOC3--20262
CCL21--21829
PLD2--22908
APOC1--23668
SERPINE10.25125055
LDLRAP1--25289

Network

GO:0048259

Network
Enrichment
NameDescriptionExternal IDs
SYNJ1synaptojanin 1 Entrez:8867  Ensembl: ENSG00000159082  HGNC: 11503  HPRD: 09182 
SH3GL2SH3-domain GRB2-like 2 Entrez:6456  HGNC: 10831  Ensembl: ENSG00000107295  HPRD: 05125 
BICD1bicaudal D homolog 1 (Drosophila) Entrez:636  Ensembl: ENSG00000151746  HGNC: 1049  HPRD: 03730 
HNRNPKheterogeneous nuclear ribonucleoprotein K Entrez:3190  HGNC: 5044  Ensembl: ENSG00000165119  HPRD: 02834 
CBLCbl proto-oncogene, E3 ubiquitin protein ligase Entrez:867  HPRD: 01320  Ensembl: ENSG00000110395  HGNC: 1541 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SYNJ1synaptojanin 1
SH3GL2SH3-domain GRB2-like 2
BICD1bicaudal D homolog 1 (Drosophila)
HNRNPKheterogeneous nuclear ribonucleoprotein K
CBLCbl proto-oncogene, E3 ubiquitin protein ligase
Query geneGeneGene descriptionEdge score
SYNJ1SYNJ1synaptojanin 1
SH3GL2SH3GL2SH3-domain GRB2-like 2
BICD1BICD1bicaudal D homolog 1 (Drosophila)
HNRNPKHNRNPKheterogeneous nuclear ribonucleoprotein K
CBLCBLCbl proto-oncogene, E3 ubiquitin protein ligase

Troyanskaya Laboratory - Princeton University