ASD

GO:0070555 response to interleukin-1 (51)

GeneInput weightStandardRank
PLCB1--148
RPS6KA5--359
SFRP1--387
PRKCI--568
VLDLR0.251574
SNCA--1667
HDAC4--696
PCSK1--898
SOX9--1970
PRKCA--1027
RELA--1142
AES--1230
RBMX--1730
XYLT1--12057
SRC--2825
EGR1--3062
CITED1--3064
SLC30A8--13644
TNFRSF11A--15293
ETS1--5943
MAPK30.2516426
FIGF--6702
CYBA--17322
CYP11A10.2518063
EDN1--9540
GHR--110098
RPS6KA4--10148
TAF9--10627
TRAF6--11055
IRF1--111641
MYLK3--12362
MMP3--13496
IRAK3--14633
SELE--14642
IRAK2--15024
EPO--20282
CHI3L1--20463
KLF2--20711
RIPK2--20830
CD380.25121442
HNMT--21489
IRAK1--21640
ANXA10.5122810
MYD88--23106
CCL2--23209
ICAM1--23720
IL1R1--23779
P2RY2--24088
MMP9--24369
IGBP1--25127
LCN2--25233

Network

GO:0070555

Network
Enrichment
NameDescriptionExternal IDs
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5 Entrez:9252  Ensembl: ENSG00000100784  HPRD: 06789  HGNC: 10434 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
PRKCIprotein kinase C, iota Entrez:5584  HGNC: 9404  HPRD: 02105  Ensembl: ENSG00000163558 
VLDLRvery low density lipoprotein receptor Entrez:7436  Ensembl: ENSG00000147852  HGNC: 12698  HPRD: 01895 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5
SFRP1secreted frizzled-related protein 1
PRKCIprotein kinase C, iota
VLDLRvery low density lipoprotein receptor
Query geneGeneGene descriptionEdge score
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
RPS6KA5RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5
SFRP1SFRP1secreted frizzled-related protein 1
PRKCIPRKCIprotein kinase C, iota
VLDLRVLDLRvery low density lipoprotein receptor

Troyanskaya Laboratory - Princeton University