ASD

GO:0006688 glycosphingolipid biosynthetic process (14)

GeneInput weightStandardRank
LARGE--1185
ST6GALNAC5--340
B4GALNT1--634
ST8SIA3--985
ST8SIA5--1410
ST8SIA20.2511618
UGCG--2062
ST8SIA1--2094
ST3GAL5--2627
GAL3ST1--4887
ST8SIA4--6549
ST8SIA6--12096
ST6GALNAC6--17669
A4GALT--23024

Network

GO:0006688

Network
Enrichment
NameDescriptionExternal IDs
LARGElike-glycosyltransferase Entrez:9215  HGNC: 6511  Ensembl: ENSG00000133424  HPRD: 04665 
ST6GALNAC5ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 Entrez:81849  HPRD: 15342  HGNC: 19342 
B4GALNT1beta-1,4-N-acetyl-galactosaminyl transferase 1 Entrez:2583  HGNC: 4117  Ensembl: ENSG00000135454  HPRD: 03525 
ST8SIA3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 Entrez:51046  HPRD: 15343  Ensembl: ENSG00000177511  HGNC: 14269 
ST8SIA5ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 Entrez:29906  Ensembl: ENSG00000101638  HGNC: 17827  HPRD: 06199 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
LARGElike-glycosyltransferase
ST6GALNAC5ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
B4GALNT1beta-1,4-N-acetyl-galactosaminyl transferase 1
ST8SIA3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
ST8SIA5ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
Query geneGeneGene descriptionEdge score
LARGELARGElike-glycosyltransferase
ST6GALNAC5ST6GALNAC5ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
B4GALNT1B4GALNT1beta-1,4-N-acetyl-galactosaminyl transferase 1
ST8SIA3ST8SIA3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
ST8SIA5ST8SIA5ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5

Troyanskaya Laboratory - Princeton University