ASD

GO:0061097 regulation of protein tyrosine kinase activity (37)

GeneInput weightStandardRank
FBXW7--198
NRG10.251936
ADORA1--960
ERBB3--1350
ADRA2A0.2511399
APP--1515
SRCIN1--1738
TGFA--1873
NCK2--3077
PAK2--4270
RAP2C--4477
WNT3A--4747
ADAM17--5323
DVL2--6546
ERRFI1--6649
ZFYVE28--7781
CD24--18102
ADRA2C--8551
EREG--9052
GHRL0.2519242
SHC1--10045
ADRA2B--10119
AFAP1L2--10424
EPGN--12503
EGF0.25112881
AGT--113305
PSEN1--18523
DOK7--19814
ZGPAT--20366
RAP2B--20526
PDGFB--21071
CBLC--21497
SNX6--22713
IBTK--22790
PSEN2--23095
GNB2L1--23282
FGFR1OP--24857

Network

GO:0061097

Network
Enrichment
NameDescriptionExternal IDs
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase Entrez:55294  HPRD: 05888  Ensembl: ENSG00000109670  HGNC: 16712 
NRG1neuregulin 1 Entrez:3084  HPRD: 00802  Ensembl: ENSG00000157168  HGNC: 7997 
ADORA1adenosine A1 receptor Entrez:134  HPRD: 00042  Ensembl: ENSG00000163485  HGNC: 262 
ERBB3v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 Entrez:2065  HGNC: 3431  Ensembl: ENSG00000065361  HPRD: 01820 
ADRA2Aadrenoceptor alpha 2A Entrez:150  HGNC: 281  HPRD: 00078  Ensembl: ENSG00000150594 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
NRG1neuregulin 1
ADORA1adenosine A1 receptor
ERBB3v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
ADRA2Aadrenoceptor alpha 2A
Query geneGeneGene descriptionEdge score
FBXW7FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
NRG1NRG1neuregulin 1
ADORA1ADORA1adenosine A1 receptor
ERBB3ERBB3v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
ADRA2AADRA2Aadrenoceptor alpha 2A

Troyanskaya Laboratory - Princeton University