ASD

GO:0045736 negative regulation of cyclin-dependent protein kinase activity (16)

GeneInput weightStandardRank
APC0.251266
CDKN1B--1162
PTEN1.011389
LATS1--2781
NR2F2--2941
MEN1--14917
MYOCD--5907
HEXIM1--5982
TFAP4--6377
CDKN1A--7714
LATS2--9736
CDKN2A--120587
HEXIM2--21545
KAT2B--23529
CDK5RAP1--24649
PLK1--25783

Network

GO:0045736

Network
Enrichment
NameDescriptionExternal IDs
APCadenomatous polyposis coli Entrez:324  HGNC: 583  HPRD: 01439  Ensembl: ENSG00000134982 
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1) Entrez:1027  HGNC: 1785  Ensembl: ENSG00000111276  HPRD: 02867 
PTENphosphatase and tensin homolog Entrez:5728  HGNC: 9588  HPRD: 03431 
LATS1large tumor suppressor kinase 1 Entrez:9113  HPRD: 09147  HGNC: 6514  Ensembl: ENSG00000131023 
NR2F2nuclear receptor subfamily 2, group F, member 2 Entrez:7026  HGNC: 7976  Ensembl: ENSG00000185551  HPRD: 00139 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
APCadenomatous polyposis coli
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)
PTENphosphatase and tensin homolog
LATS1large tumor suppressor kinase 1
NR2F2nuclear receptor subfamily 2, group F, member 2
Query geneGeneGene descriptionEdge score
APCAPCadenomatous polyposis coli
CDKN1BCDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)
PTENPTENphosphatase and tensin homolog
LATS1LATS1large tumor suppressor kinase 1
NR2F2NR2F2nuclear receptor subfamily 2, group F, member 2

Troyanskaya Laboratory - Princeton University