ASD

GO:0031663 lipopolysaccharide-mediated signaling pathway (17)

GeneInput weightStandardRank
PRKCE--204
MAPK1--1128
MTDH--1461
MAPK14--3975
IRF3--4175
NFKBIA--5569
MAPK30.2516426
TLR4--112795
SCARB1--13530
IRAK2--15024
TLR2--119246
LBP--20559
RIPK2--20830
IRAK1--21640
TICAM1--21880
MYD88--23106
LY96--23247

Network

GO:0031663

Network
Enrichment
NameDescriptionExternal IDs
PRKCEprotein kinase C, epsilon Entrez:5581  HPRD: 01500  HGNC: 9401  Ensembl: ENSG00000171132 
MAPK1mitogen-activated protein kinase 1 Entrez:5594  HPRD: 01496  Ensembl: ENSG00000100030  HGNC: 6871 
MTDHmetadherin Entrez:92140  Ensembl: ENSG00000147649  HGNC: 29608  HPRD: 17459 
MAPK14mitogen-activated protein kinase 14 Entrez:1432  HGNC: 6876  Ensembl: ENSG00000112062  HPRD: 02619 
IRF3interferon regulatory factor 3 Entrez:3661  HPRD: 04769  HGNC: 6118  Ensembl: ENSG00000126456 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PRKCEprotein kinase C, epsilon
MAPK1mitogen-activated protein kinase 1
MTDHmetadherin
MAPK14mitogen-activated protein kinase 14
IRF3interferon regulatory factor 3
Query geneGeneGene descriptionEdge score
PRKCEPRKCEprotein kinase C, epsilon
MAPK1MAPK1mitogen-activated protein kinase 1
MTDHMTDHmetadherin
MAPK14MAPK14mitogen-activated protein kinase 14
IRF3IRF3interferon regulatory factor 3

Troyanskaya Laboratory - Princeton University