ASD

GO:0006370 mRNA capping (29)

GeneInput weightStandardRank
POLR2B--327
POLR2E--720
POLR2A--1630
SUPT5H--1754
GTF2F1--1876
RNMT--1890
RNGTT--1998
CDK7--3072
POLR2J--3075
POLR2L--3908
CCNH--4961
POLR2G--6511
POLR2K--6853
ERCC3--17110
GTF2H1--7370
POLR2I--9926
POLR2F--11417
GTF2H3--13304
CMTR1--18629
POLR2C--21170
MNAT1--21615
ERCC2--121804
NCBP2--23216
POLR2H--23670
GTF2F2--23723
GTF2H4--24388
GTF2H2--25399
POLR2D--25479
NCBP1--25523

Network

GO:0006370

Network
Enrichment
NameDescriptionExternal IDs
POLR2Bpolymerase (RNA) II (DNA directed) polypeptide B, 140kDa Entrez:5431  HPRD: 15943  Ensembl: ENSG00000047315  HGNC: 9188 
POLR2Epolymerase (RNA) II (DNA directed) polypeptide E, 25kDa Entrez:5434  HGNC: 9192  HPRD: 15946 
POLR2Apolymerase (RNA) II (DNA directed) polypeptide A, 220kDa Entrez:5430  HGNC: 9187  Ensembl: ENSG00000181222  HPRD: 08916 
SUPT5Hsuppressor of Ty 5 homolog (S. cerevisiae) Entrez:6829  HPRD: 03655  Ensembl: ENSG00000196235  HGNC: 11469 
GTF2F1general transcription factor IIF, polypeptide 1, 74kDa Entrez:2962  Ensembl: ENSG00000125651  HPRD: 01803  HGNC: 4652 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
POLR2Bpolymerase (RNA) II (DNA directed) polypeptide B, 140kDa
POLR2Epolymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR2Apolymerase (RNA) II (DNA directed) polypeptide A, 220kDa
SUPT5Hsuppressor of Ty 5 homolog (S. cerevisiae)
GTF2F1general transcription factor IIF, polypeptide 1, 74kDa
Query geneGeneGene descriptionEdge score
POLR2BPOLR2Bpolymerase (RNA) II (DNA directed) polypeptide B, 140kDa
POLR2EPOLR2Epolymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR2APOLR2Apolymerase (RNA) II (DNA directed) polypeptide A, 220kDa
SUPT5HSUPT5Hsuppressor of Ty 5 homolog (S. cerevisiae)
GTF2F1GTF2F1general transcription factor IIF, polypeptide 1, 74kDa

Troyanskaya Laboratory - Princeton University