ASD

GO:0048008 platelet-derived growth factor receptor signaling pathway (21)

GeneInput weightStandardRank
PDGFRA--1320
SCHIP1--1178
GAB1--1198
TIPARP--2888
ZFAND5--3128
PDGFA--3731
PLEKHA1--3930
VEGFA0.2514087
PDGFC--6530
RAPGEF1--7926
PTPRJ--19136
TXNIP--10069
CSRNP1--11067
BCAR1--12026
RGS14--12999
SGPL1--15362
IQCJ-SCHIP1--17789
PDGFB--21071
PLAT--22444
PDGFRB--23242
PDGFRL--124214

Network

GO:0048008

Network
Enrichment
NameDescriptionExternal IDs
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide Entrez:5156  Ensembl: ENSG00000134853  HPRD: 01429  HGNC: 8803 
SCHIP1schwannomin interacting protein 1 Entrez:29970  HPRD: 15302  HGNC: 15678  Ensembl: ENSG00000151967 
GAB1GRB2-associated binding protein 1 Entrez:2549  HPRD: 05116  Ensembl: ENSG00000109458  HGNC: 4066 
TIPARPTCDD-inducible poly(ADP-ribose) polymerase Entrez:25976  Ensembl: ENSG00000163659  HGNC: 23696  HPRD: 18192 
ZFAND5zinc finger, AN1-type domain 5 Entrez:7763  HPRD: 05302  HGNC: 13008  Ensembl: ENSG00000107372 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide
SCHIP1schwannomin interacting protein 1
GAB1GRB2-associated binding protein 1
TIPARPTCDD-inducible poly(ADP-ribose) polymerase
ZFAND5zinc finger, AN1-type domain 5
Query geneGeneGene descriptionEdge score
PDGFRAPDGFRAplatelet-derived growth factor receptor, alpha polypeptide
SCHIP1SCHIP1schwannomin interacting protein 1
GAB1GAB1GRB2-associated binding protein 1
TIPARPTIPARPTCDD-inducible poly(ADP-ribose) polymerase
ZFAND5ZFAND5zinc finger, AN1-type domain 5

Troyanskaya Laboratory - Princeton University