ASD

GO:0050858 negative regulation of antigen receptor-mediated signaling pathway (9)

GeneInput weightStandardRank
CBLB--1161
THY1--1580
ELF1--2054
PRNP--15418
DUSP3--8506
PTPRJ--19136
UBASH3A--12815
PAWR--13478
PTPN22--121899

Network

GO:0050858

Network
Enrichment
NameDescriptionExternal IDs
CBLBCbl proto-oncogene B, E3 ubiquitin protein ligase Entrez:868  HPRD: 05136  HGNC: 1542  Ensembl: ENSG00000114423 
THY1Thy-1 cell surface antigen Entrez:7070  HGNC: 11801  HPRD: 01769 
ELF1E74-like factor 1 (ets domain transcription factor) Entrez:1997  HGNC: 3316  Ensembl: ENSG00000120690  HPRD: 01808 
PRNPprion protein Entrez:5621  Ensembl: ENSG00000171867  HGNC: 9449  HPRD: 01453 
DUSP3dual specificity phosphatase 3 Entrez:1845  Ensembl: ENSG00000108861  HGNC: 3069  HPRD: 02553 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CBLBCbl proto-oncogene B, E3 ubiquitin protein ligase
THY1Thy-1 cell surface antigen
ELF1E74-like factor 1 (ets domain transcription factor)
PRNPprion protein
DUSP3dual specificity phosphatase 3
Query geneGeneGene descriptionEdge score
CBLBCBLBCbl proto-oncogene B, E3 ubiquitin protein ligase
THY1THY1Thy-1 cell surface antigen
ELF1ELF1E74-like factor 1 (ets domain transcription factor)
PRNPPRNPprion protein
DUSP3DUSP3dual specificity phosphatase 3

Troyanskaya Laboratory - Princeton University