ASD

GO:0048172 regulation of short-term neuronal synaptic plasticity (8)

GeneInput weightStandardRank
GRIK20.51232
GRIK1--481
UNC13A--1859
PPFIA3--2061
SYP--3133
SYNGR1--4153
SHISA9--12388
UNC13B--13412

Network

GO:0048172

Network
Enrichment
NameDescriptionExternal IDs
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  Ensembl: ENSG00000164418  HGNC: 4580  HPRD: 00692 
GRIK1glutamate receptor, ionotropic, kainate 1 Entrez:2897  HGNC: 4579  HPRD: 00693  Ensembl: ENSG00000171189 
UNC13Aunc-13 homolog A (C. elegans) Entrez:23025  Ensembl: ENSG00000130477  HGNC: 23150 
PPFIA3protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 Entrez:8541  HPRD: 04393  Ensembl: ENSG00000177380  HGNC: 9247 
SYPsynaptophysin Entrez:6855  HGNC: 11506  HPRD: 02435  Ensembl: ENSG00000102003 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GRIK2glutamate receptor, ionotropic, kainate 2
GRIK1glutamate receptor, ionotropic, kainate 1
UNC13Aunc-13 homolog A (C. elegans)
PPFIA3protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
SYPsynaptophysin
Query geneGeneGene descriptionEdge score
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2
GRIK1GRIK1glutamate receptor, ionotropic, kainate 1
UNC13AUNC13Aunc-13 homolog A (C. elegans)
PPFIA3PPFIA3protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
SYPSYPsynaptophysin

Troyanskaya Laboratory - Princeton University