ASD

GO:0031641 regulation of myelination (10)

GeneInput weightStandardRank
CDH2--164
DICER1--1762
MYRF--2677
HES5--4919
CTNNB10.519066
IFNG--112827
TG--18556
EIF2AK3--20456
RNF10--22383
KLK8--22593

Network

GO:0031641

Network
Enrichment
NameDescriptionExternal IDs
CDH2cadherin 2, type 1, N-cadherin (neuronal) Entrez:1000  Ensembl: ENSG00000170558  HGNC: 1759  HPRD: 00226 
DICER1dicer 1, ribonuclease type III Entrez:23405  HGNC: 17098  Ensembl: ENSG00000100697  HPRD: 05875 
MYRFmyelin regulatory factor Entrez:745  HPRD: 12213  HGNC: 1181  Ensembl: ENSG00000124920 
HES5hairy and enhancer of split 5 (Drosophila) Entrez:388585  Ensembl: ENSG00000197921  HGNC: 19764  HPRD: 16240 
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa Entrez:1499  HGNC: 2514  HPRD: 00286  Ensembl: ENSG00000168036 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CDH2cadherin 2, type 1, N-cadherin (neuronal)
DICER1dicer 1, ribonuclease type III
MYRFmyelin regulatory factor
HES5hairy and enhancer of split 5 (Drosophila)
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa
Query geneGeneGene descriptionEdge score
CDH2CDH2cadherin 2, type 1, N-cadherin (neuronal)
DICER1DICER1dicer 1, ribonuclease type III
MYRFMYRFmyelin regulatory factor
HES5HES5hairy and enhancer of split 5 (Drosophila)
CTNNB1CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa

Troyanskaya Laboratory - Princeton University