ASD

GO:0034260 negative regulation of GTPase activity (8)

GeneInput weightStandardRank
PTPRN20.251405
SPRY2--1454
FZD10--2957
DAB2IP--3482
ARL2--5930
SPRY1--10636
FICD--13795
GMIP--22274

Network

GO:0034260

Network
Enrichment
NameDescriptionExternal IDs
PTPRN2protein tyrosine phosphatase, receptor type, N polypeptide 2 Entrez:5799  Ensembl: ENSG00000155093  HGNC: 9677  HPRD: 03413 
SPRY2sprouty homolog 2 (Drosophila) Entrez:10253  Ensembl: ENSG00000136158  HPRD: 03916  HGNC: 11270 
FZD10frizzled family receptor 10 Entrez:11211  HGNC: 4039  HPRD: 05853  Ensembl: ENSG00000111432 
DAB2IPDAB2 interacting protein Entrez:153090  Ensembl: ENSG00000136848  HGNC: 17294  HPRD: 09903 
ARL2ADP-ribosylation factor-like 2 Entrez:402  HPRD: 11869  Ensembl: ENSG00000213465  HGNC: 693 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PTPRN2protein tyrosine phosphatase, receptor type, N polypeptide 2
SPRY2sprouty homolog 2 (Drosophila)
FZD10frizzled family receptor 10
DAB2IPDAB2 interacting protein
ARL2ADP-ribosylation factor-like 2
Query geneGeneGene descriptionEdge score
PTPRN2PTPRN2protein tyrosine phosphatase, receptor type, N polypeptide 2
SPRY2SPRY2sprouty homolog 2 (Drosophila)
FZD10FZD10frizzled family receptor 10
DAB2IPDAB2IPDAB2 interacting protein
ARL2ARL2ADP-ribosylation factor-like 2

Troyanskaya Laboratory - Princeton University