ASD

GO:0009948 anterior/posterior axis specification (34)

GeneInput weightStandardRank
LRP6--279
PGAP1--711
SMAD4--821
PCSK6--1035
OTX2--11916
EPB41L5--2335
LHX1--2560
FOXA2--2645
SRF--2841
SKI--2904
TBX3--2958
NODAL--13149
T--3286
WNT5A--3319
HOXB6--4560
WNT3--4613
TDGF1--6132
BMP4--16499
CER1--6956
RNF2--7154
FRS2--7173
HOXD8--7316
TDRD5--7375
RIPPLY2--7657
WNT8A--7814
GPC3--18430
CTNNB10.519066
RIPPLY1--9472
LDB1--10693
GDF3--110819
TCF7L1--12273
WLS--15707
PLD6--21953
FZD5--23249

Network

GO:0009948

Network
Enrichment
NameDescriptionExternal IDs
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
PGAP1post-GPI attachment to proteins 1 Entrez:80055  HGNC: 25712  HPRD: 10147 
SMAD4SMAD family member 4 Entrez:4089  Ensembl: ENSG00000141646  HGNC: 6770  HPRD: 02995 
PCSK6proprotein convertase subtilisin/kexin type 6 Entrez:5046  HPRD: 01329  HGNC: 8569  Ensembl: ENSG00000140479 
OTX2orthodenticle homeobox 2 Entrez:5015  HGNC: 8522  HPRD: 07190  Ensembl: ENSG00000165588 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
LRP6low density lipoprotein receptor-related protein 6
PGAP1post-GPI attachment to proteins 1
SMAD4SMAD family member 4
PCSK6proprotein convertase subtilisin/kexin type 6
OTX2orthodenticle homeobox 2
Query geneGeneGene descriptionEdge score
LRP6LRP6low density lipoprotein receptor-related protein 6
PGAP1PGAP1post-GPI attachment to proteins 1
SMAD4SMAD4SMAD family member 4
PCSK6PCSK6proprotein convertase subtilisin/kexin type 6
OTX2OTX2orthodenticle homeobox 2

Troyanskaya Laboratory - Princeton University