ASD

GO:0010718 positive regulation of epithelial to mesenchymal transition (20)

GeneInput weightStandardRank
SMAD4--821
SMAD3--823
TGFB2--834
LEF1--1499
EPB41L5--2335
SMAD2--2694
BCL9L--2729
NOTCH1--12865
TCF7L20.513548
AXIN2--14260
ZNF703--5031
TWIST1--16980
BAMBI--8550
CTNNB10.519066
SNAI1--9198
TGFB3--113097
TGFB10.25120135
TGFB1I1--23709
COL1A1--124140
WWTR1--24317

Network

GO:0010718

Network
Enrichment
NameDescriptionExternal IDs
SMAD4SMAD family member 4 Entrez:4089  Ensembl: ENSG00000141646  HGNC: 6770  HPRD: 02995 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
TGFB2transforming growth factor, beta 2 Entrez:7042  HGNC: 11768  Ensembl: ENSG00000092969  HPRD: 01828 
LEF1lymphoid enhancer-binding factor 1 Entrez:51176  HGNC: 6551  Ensembl: ENSG00000138795  HPRD: 01075 
EPB41L5erythrocyte membrane protein band 4.1 like 5 Entrez:57669  Ensembl: ENSG00000115109  HGNC: 19819  HPRD: 13273 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SMAD4SMAD family member 4
SMAD3SMAD family member 3
TGFB2transforming growth factor, beta 2
LEF1lymphoid enhancer-binding factor 1
EPB41L5erythrocyte membrane protein band 4.1 like 5
Query geneGeneGene descriptionEdge score
SMAD4SMAD4SMAD family member 4
SMAD3SMAD3SMAD family member 3
TGFB2TGFB2transforming growth factor, beta 2
LEF1LEF1lymphoid enhancer-binding factor 1
EPB41L5EPB41L5erythrocyte membrane protein band 4.1 like 5

Troyanskaya Laboratory - Princeton University