ASD

GO:0050796 regulation of insulin secretion (117)

GeneInput weightStandardRank
SNAP250.25126
CNR10.25129
VAMP2--33
NEUROD1--1127
KCNB1--179
PRKCE--204
PPP3CA--244
SOX4--250
CACNA1A--1270
PDE8B--1287
CACNA1D0.51293
SFRP1--387
ABCC8--1406
SYT5--444
MARCKS--492
STX1A0.251512
NNAT--543
PRKACB--584
ITPR1--1597
CACNA1E--612
MGEA5--732
CACNA2D2--744
STXBP1--769
CACNA1C--1807
PCSK1--898
RAPGEF40.251904
PRKCA--1027
PRKAR1B--1257
BAD--1290
IRS2--11300
IRS1--11374
ADRA2A0.2511399
RAP1B--1455
RFX3--1523
SYT7--1536
CHRM3--1725
AKAP5--1759
GNAS--11842
CARTPT0.2511957
ISL1--1974
PFKL--2192
PRKAR2B--2211
PRKAR1A--12428
GHSR0.2512467
GCK--12660
KCNS3--2730
SLC25A6--2820
INHBB--2842
PDE4C--3021
TRH--3416
RBP4--3448
SLC25A5--3511
TCF7L20.513548
SLC30A8--13644
DRD20.2513749
PDE3B--3819
ACVR1C--3963
PRKACG--4112
GLUD1--14146
SLC2A2--4553
G6PC2--4647
SIRT4--4652
NKX6-1--4665
GCG--5190
CAPN10--5208
RFX6--5466
SYT9--5512
OXCT1--5813
MTNR1B0.2516286
PFKFB2--6327
GIP--6352
KCNC2--6855
KCNQ1--17724
SYTL4--7863
ITPR2--8066
SPCS2--8185
RAPGEF3--8436
ADRA2C--8551
AACS--9143
KCNJ11--19151
GHRL0.2519242
LRP5--19420
PRKACA--9630
REST--9779
GLP1R--9893
GIPR--10369
UCN3--10665
IL1B--110818
DOC2B--11084
FFAR1--11393
PRKAR2A--11450
SERP1--11460
NOS20.25111577
BLK--111743
LEP0.25111864
IQGAP1--12240
IFNG--112827
RAP1A--13091
PSMD9--13911
KCNG2--14521
TNF0.25115243
SLC25A4--115900
SREBF1--19464
FAM3D--20640
SEC11A--20786
SLC2A1--21288
NR0B2--121425
CD380.25121442
ITPR3--21697
HMGN3--21870
INS--122047
SPCS1--22815
HNF4A--122965
CPT1A--23997
SEC11C--24070
HADH--125329
SPCS3--25638

Network

GO:0050796

Network
Enrichment
NameDescriptionExternal IDs
SNAP25synaptosomal-associated protein, 25kDa Entrez:6616  Ensembl: ENSG00000132639  HPRD: 02637  HGNC: 11132 
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2) Entrez:6844  HGNC: 12643  HPRD: 01717  Ensembl: ENSG00000220205 
NEUROD1neuronal differentiation 1 Entrez:4760  HPRD: 03428  HGNC: 7762  Ensembl: ENSG00000162992 
KCNB1potassium voltage-gated channel, Shab-related subfamily, member 1 Entrez:3745  HPRD: 08983  HGNC: 6231 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SNAP25synaptosomal-associated protein, 25kDa
CNR1cannabinoid receptor 1 (brain)
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
NEUROD1neuronal differentiation 1
KCNB1potassium voltage-gated channel, Shab-related subfamily, member 1
Query geneGeneGene descriptionEdge score
SNAP25SNAP25synaptosomal-associated protein, 25kDa
CNR1CNR1cannabinoid receptor 1 (brain)
VAMP2VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
NEUROD1NEUROD1neuronal differentiation 1
KCNB1KCNB1potassium voltage-gated channel, Shab-related subfamily, member 1

Troyanskaya Laboratory - Princeton University