ASD

GO:0030036 actin cytoskeleton organization (265)

GeneInput weightStandardRank
KRAS--157
PAFAH1B10.25174
ABR--160
PDGFRA--1320
RAP2A--324
MYH10--366
NF10.251372
DBN1--385
GAS7--398
RICTOR--537
PFN1--548
PFN2--551
PRKCI--568
MTSS1--594
ARHGEF11--705
SIPA1L1--716
ARPC1A--901
ABI2--986
FHOD3--989
PROX1--997
PPP1R9A--1028
WASF3--1046
CUL31.011093
EPB41L1--1108
CORO2B--1123
CDC42--1138
FGD1--11182
DYNLL1--1191
DLC1--1282
AMOT--1325
ENAH--1348
DAAM1--1384
ADRA2A0.2511399
CDC42BPA--1453
DMTN--1465
TNIK--1531
WASF1--1544
PRKG1--1553
LIMCH1--1586
RAC1--1617
TAOK20.2511633
PDPK1--1740
ARHGEF2--1819
BCR--11839
NISCH--1913
ELMO1--1914
FMNL20.2511944
FMN2--1970
TNFAIP1--2123
TMSB10--2139
SSH2--2172
CAPZB--2179
WASL--2257
RHOA--2292
EPB41L5--2335
ADD2--2388
ABL1--2404
ARPC5--2454
GHSR0.2512467
DAAM2--2511
RND3--2538
CAP1--2541
BCL6--2550
KLHL1--2570
FGF7--2591
ACTN4--12685
CRK--2713
ALDOA0.2512739
CDC42BPB0.512749
PREX1--2760
MEF2A--2837
SRF--2841
ADD1--12876
ARPC4--2880
TMSB15A--2947
CYTH2--3020
PTK2B--3063
NCK2--3077
FSCN1--3099
EVL--3103
KCTD130.2513132
TMSB15B--3139
ARHGEF17--3189
CDK50.2513194
FERMT2--3249
ARFIP2--3261
ARF6--3317
EPB41L3--3441
NPHP4--13630
FMNL3--3643
ARHGAP26--13662
PDGFA--3731
DLG1--3822
ITGB1--3903
SSH1--4066
LPIN1--4092
CFL1--4162
RALA--4169
ARHGEF18--4257
LIMK1--4265
FLNA--14285
CORO1C--4370
ROCK1--4378
CAPZA2--4483
FGF10--14532
SH2B2--4634
INPPL1--4681
PACSIN2--4790
ERMN--4859
CAPZA1--4983
HRAS0.2515086
BMP10--5102
CAPN10--5208
SPTBN5--5319
ARHGAP6--5374
RND1--5515
TTN--15620
ACTN1--5704
JMY--5725
NF2--15991
PLA2G1B--6059
RAC3--6123
LLGL1--6207
ATP2C1--16243
RHOG--6279
DIAPH2--16281
TMSB4X--6302
DSTN--6316
SORBS1--6411
ABI1--6421
TESK2--6506
OPHN10.516584
CNN3--6611
SPTA1--16958
SHROOM4--7165
KLHL17--7239
LRRC16A--7272
NEDD9--7432
FGD4--17457
MRAS--7483
ACTG1--17566
FOXJ1--7628
EPB41--17811
VASP--7880
RHOJ--7924
CAPZA3--8396
MYH9--18434
NKX2-50.2518486
FGD3--8790
MYL2--18834
PFN4--8895
EZR--8959
OBSL1--9074
GHRL0.2519242
FMNL1--9287
MYOZ1--9335
AQP2--9426
CCL11--9615
SCIN--9620
TRPM7--9799
XIRP1--10027
SHC1--10045
TMOD1--10393
CRYAA--10509
SHROOM1--10562
FGD5--10619
WASH3P--10817
CDC42BPG--10897
TLN1--10904
WASH2P--11022
FMN1--11234
XIRP20.25111334
ANTXR1--11387
DTNBP1--11492
CCKAR--11747
BCAR1--12026
EPB41L2--12059
PDLIM7--12078
NPHP1--112095
CORO6--12182
FGD6--12199
FAT1--12319
MYLK3--12362
WASF2--12417
ACTA1--12431
PDXP--12453
RHOU--12495
ACTC1--112547
CORO2A--12635
ESPN--112835
FLNB--112875
CXCL1--13296
FHDC1--13408
PAWR--13478
ARHGAP17--13491
TMSB4Y--13524
PTK7--13643
MYH6--113823
WASH6P--13829
PFN3--14063
TMSB4XP8--14081
RHOQ--14092
NRAS--114119
CORO1B--14160
BIN3--14801
FSCN2--115241
PPARGC1B--115356
WASH1--15718
TRPV4--115988
NEURL2--16307
TMSB4XP4--17717
WASH4P--17760
NUAK2--18734
FHL3--19425
CDC42EP2--19500
JAK2--119561
ARRB1--19906
SDCBP--19967
FGD2--20103
CORO1A--20339
CAPN3--120523
PDGFB--21071
EPS8--21085
GRID2IP--21156
HSP90B1--21432
DIAPH3--21753
PDLIM3--21762
SLC9A3R1--21898
TCAP--122131
VIL10.5122243
AQP1--22433
GPR65--22555
DIAPH1--122599
KPTN--22671
S100A9--22828
INF2--122981
ARHGDIB--23104
CNN1--23141
PDGFRB--23242
RHOF--23397
MYH11--123442
LCP1--23490
AIF1--23667
DOCK2--23744
NCKAP1L--23771
TRIP10--23849
GSN--124007
INPP5K--24055
TRIOBP--124113
PLEK--24240
TPM1--124247
PLEK2--24281
CALD1--24393
WAS--124487
KRT19--24520
LIMA1--24553
WIPF1--24668
RAC2--24787
FHOD1--24802
ANG--124879
ARAP1--24899
RACGAP1--24932
TNXB--124960
CNN2--25083
EHD2--25615

Network

GO:0030036

Network
Enrichment
NameDescriptionExternal IDs
KRASKirsten rat sarcoma viral oncogene homolog Entrez:3845  Ensembl: ENSG00000133703  HGNC: 6407  HPRD: 01817 
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) Entrez:5048  HGNC: 8574  HPRD: 03329  Ensembl: ENSG00000007168 
ABRactive BCR-related Entrez:29  HGNC: 81  HPRD: 02649  Ensembl: ENSG00000159842 
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide Entrez:5156  Ensembl: ENSG00000134853  HPRD: 01429  HGNC: 8803 
RAP2ARAP2A, member of RAS oncogene family Entrez:5911  HGNC: 9861  HPRD: 01547 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
KRASKirsten rat sarcoma viral oncogene homolog
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
ABRactive BCR-related
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide
RAP2ARAP2A, member of RAS oncogene family
Query geneGeneGene descriptionEdge score
KRASKRASKirsten rat sarcoma viral oncogene homolog
PAFAH1B1PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
ABRABRactive BCR-related
PDGFRAPDGFRAplatelet-derived growth factor receptor, alpha polypeptide
RAP2ARAP2ARAP2A, member of RAS oncogene family

Troyanskaya Laboratory - Princeton University