ASD

GO:0060159 regulation of dopamine receptor signaling pathway (6)

GeneInput weightStandardRank
PALM--1501
DRD20.2513749
DRD30.2514349
LRRK2--18802
DTNBP1--11492
CAV2--25271

Network

GO:0060159

Network
Enrichment
NameDescriptionExternal IDs
PALMparalemmin Entrez:5064  HGNC: 8594  Ensembl: ENSG00000099864  HPRD: 09734 
DRD2dopamine receptor D2 Entrez:1813  HPRD: 00539  Ensembl: ENSG00000149295  HGNC: 3023 
DRD3dopamine receptor D3 Entrez:1814  HGNC: 3024  Ensembl: ENSG00000151577  HPRD: 00540 
LRRK2leucine-rich repeat kinase 2 Entrez:120892  HGNC: 18618  Ensembl: ENSG00000188906 
DTNBP1dystrobrevin binding protein 1 Entrez:84062  Ensembl: ENSG00000047579  HGNC: 17328  HPRD: 06190 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PALMparalemmin
DRD2dopamine receptor D2
DRD3dopamine receptor D3
LRRK2leucine-rich repeat kinase 2
DTNBP1dystrobrevin binding protein 1
Query geneGeneGene descriptionEdge score
PALMPALMparalemmin
DRD2DRD2dopamine receptor D2
DRD3DRD3dopamine receptor D3
LRRK2LRRK2leucine-rich repeat kinase 2
DTNBP1DTNBP1dystrobrevin binding protein 1

Troyanskaya Laboratory - Princeton University