ASD

GO:0035567 non-canonical Wnt receptor signaling pathway (24)

GeneInput weightStandardRank
SFRP1--387
FZD7--1357
RAC1--1617
WNT2B--1673
VANGL2--1793
DVL3--2090
FZD4--12229
FZD10--2957
WNT5A--3319
WNT1--4383
WNT3--4613
WNT3A--4747
DVL2--6546
WNT7A--7312
GRHL3--7409
WNT11--7820
WNT9B--8217
WNT5B--15534
FZD2--16930
DVL1P1--18731
DVL1--18924
FZD6--19921
FZD1--20775
WNT4--21809

Network

GO:0035567

Network
Enrichment
NameDescriptionExternal IDs
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
FZD7frizzled family receptor 7 Entrez:8324  HGNC: 4045  HPRD: 04560  Ensembl: ENSG00000155760 
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Entrez:5879  Ensembl: ENSG00000136238  HPRD: 03627  HGNC: 9801 
WNT2Bwingless-type MMTV integration site family, member 2B Entrez:7482  Ensembl: ENSG00000134245  HGNC: 12781  HPRD: 03574 
VANGL2VANGL planar cell polarity protein 2 Entrez:57216  Ensembl: ENSG00000162738  HGNC: 15511  HPRD: 02758 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SFRP1secreted frizzled-related protein 1
FZD7frizzled family receptor 7
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
WNT2Bwingless-type MMTV integration site family, member 2B
VANGL2VANGL planar cell polarity protein 2
Query geneGeneGene descriptionEdge score
SFRP1SFRP1secreted frizzled-related protein 1
FZD7FZD7frizzled family receptor 7
RAC1RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
WNT2BWNT2Bwingless-type MMTV integration site family, member 2B
VANGL2VANGL2VANGL planar cell polarity protein 2

Troyanskaya Laboratory - Princeton University