ASD

GO:0022412 cellular process involved in reproduction in multicellular organism (19)

GeneInput weightStandardRank
PAFAH1B10.25174
SPAM1--772
CHN2--2347
CRISP1--2892
ADAM2--4234
TBPL1--6418
IHH--17160
AGFG1--8117
PVRL2--8977
IZUMO1--10533
HYAL4--10855
FABP9--13169
ZP3--17443
ROPN1B--19629
CASC5--20342
SERPINA5--20717
VMO1--21189
CATSPER1--21782
CD9--22906

Network

GO:0022412

Network
Enrichment
NameDescriptionExternal IDs
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) Entrez:5048  HGNC: 8574  HPRD: 03329  Ensembl: ENSG00000007168 
SPAM1sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) Entrez:6677  HGNC: 11217  Ensembl: ENSG00000106304  HPRD: 02958 
CHN2chimerin 2 Entrez:1124  Ensembl: ENSG00000106069  HPRD: 04173  HGNC: 1944 
CRISP1cysteine-rich secretory protein 1 Entrez:167  Ensembl: ENSG00000124812  HGNC: 304  HPRD: 03118 
ADAM2ADAM metallopeptidase domain 2 Entrez:2515  HPRD: 03322  HGNC: 198  Ensembl: ENSG00000104755 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
SPAM1sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
CHN2chimerin 2
CRISP1cysteine-rich secretory protein 1
ADAM2ADAM metallopeptidase domain 2
Query geneGeneGene descriptionEdge score
PAFAH1B1PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
SPAM1SPAM1sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
CHN2CHN2chimerin 2
CRISP1CRISP1cysteine-rich secretory protein 1
ADAM2ADAM2ADAM metallopeptidase domain 2

Troyanskaya Laboratory - Princeton University