ASD

GO:0071359 cellular response to dsRNA (25)

GeneInput weightStandardRank
GRIN2A0.25166
AGO2--490
ZCCHC11--737
DICER1--1762
GRIN2B1.01763
SMAD3--823
SMAD1--1872
SMAD2--2694
IRF3--4175
IFNB1--5250
LIN28B--5378
LIN28A--7070
DGCR8--8286
PRKRA--9728
IRF1--111641
SRRT--12400
SNIP1--12657
DROSHA--14199
ZC3HAV1--19641
TLR3--22478
RBM3--22670
MAVS--23348
IFIT1--24398
TMEM173--24599
TARBP2--24667

Network

GO:0071359

Network
Enrichment
NameDescriptionExternal IDs
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
AGO2argonaute RISC catalytic component 2 Entrez:27161  HGNC: 3263  HPRD: 06943  Ensembl: ENSG00000123908 
ZCCHC11zinc finger, CCHC domain containing 11 Entrez:23318  HGNC: 28981  Ensembl: ENSG00000134744  HPRD: 15700 
DICER1dicer 1, ribonuclease type III Entrez:23405  HGNC: 17098  Ensembl: ENSG00000100697  HPRD: 05875 
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B Entrez:2904  Ensembl: ENSG00000150086  HPRD: 00697  HGNC: 4586 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
AGO2argonaute RISC catalytic component 2
ZCCHC11zinc finger, CCHC domain containing 11
DICER1dicer 1, ribonuclease type III
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B
Query geneGeneGene descriptionEdge score
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
AGO2AGO2argonaute RISC catalytic component 2
ZCCHC11ZCCHC11zinc finger, CCHC domain containing 11
DICER1DICER1dicer 1, ribonuclease type III
GRIN2BGRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B

Troyanskaya Laboratory - Princeton University