ASD

GO:0048662 negative regulation of smooth muscle cell proliferation (22)

GeneInput weightStandardRank
PIK3R10.251150
SF1--2557
IGFBP5--3306
TRIB1--3431
IL12B--3596
KLF4--3609
TNFAIP3--4469
CTNNBIP1--5675
ADIPOQ0.2516032
ILK--7305
NPPB--7334
IL12A--10482
MFN2--111607
IFNG--112827
COMT0.25113475
NDRG2--19677
NOS3--20542
IGFBP3--22342
IL15--23090
HMOX1--23938
ANG--124879
NPR1--24948

Network

GO:0048662

Network
Enrichment
NameDescriptionExternal IDs
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
SF1splicing factor 1 Entrez:7536  Ensembl: ENSG00000168066  HPRD: 03306  HGNC: 12950 
IGFBP5insulin-like growth factor binding protein 5 Entrez:3488  HGNC: 5474  Ensembl: ENSG00000115461  HPRD: 00901 
TRIB1tribbles homolog 1 (Drosophila) Entrez:10221  HPRD: 09863  Ensembl: ENSG00000173334  HGNC: 16891 
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) Entrez:3593  HGNC: 5970  Ensembl: ENSG00000113302  HPRD: 01194 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
SF1splicing factor 1
IGFBP5insulin-like growth factor binding protein 5
TRIB1tribbles homolog 1 (Drosophila)
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
Query geneGeneGene descriptionEdge score
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
SF1SF1splicing factor 1
IGFBP5IGFBP5insulin-like growth factor binding protein 5
TRIB1TRIB1tribbles homolog 1 (Drosophila)
IL12BIL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)

Troyanskaya Laboratory - Princeton University