GO:0046426 negative regulation of JAK-STAT cascade (9)

GeneInput weightStandardRank
PPP2CA--20
NEUROD1--1127
HGS--152
PPP2R1A--1163
NF2--15991
SOCS1--9583
IRF1--111641
HNF4A--122965
CAV1--125381

Network

GO:0046426

Network
Enrichment
NameDescriptionExternal IDs
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme Entrez:5515  HGNC: 9299  HPRD: 08912 
NEUROD1neuronal differentiation 1 Entrez:4760  HPRD: 03428  HGNC: 7762  Ensembl: ENSG00000162992 
HGShepatocyte growth factor-regulated tyrosine kinase substrate Entrez:9146  Ensembl: ENSG00000185359  HPRD: 05085  HGNC: 4897 
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha Entrez:5518  HPRD: 16184  HGNC: 9302 
NF2neurofibromin 2 (merlin) Entrez:4771  Ensembl: ENSG00000186575  HGNC: 7773  HPRD: 06980 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
NEUROD1neuronal differentiation 1
HGShepatocyte growth factor-regulated tyrosine kinase substrate
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha
NF2neurofibromin 2 (merlin)
Query geneGeneGene descriptionEdge score
PPP2CAPPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
NEUROD1NEUROD1neuronal differentiation 1
HGSHGShepatocyte growth factor-regulated tyrosine kinase substrate
PPP2R1APPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha
NF2NF2neurofibromin 2 (merlin)