ASD

GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity (10)

GeneInput weightStandardRank
CACNG3--158
NLGN10.251276
MAPK8IP2--418
CACNG4--1342
CACNG2--1460
CNIH3--2659
CNIH2--4797
CACNG5--4873
CACNG8--7376
CACNG7--9025

Network

GO:2000311

Network
Enrichment
NameDescriptionExternal IDs
CACNG3calcium channel, voltage-dependent, gamma subunit 3 Entrez:10368  HGNC: 1407  Ensembl: ENSG00000006116  HPRD: 05910 
NLGN1neuroligin 1 Entrez:22871  HGNC: 14291  HPRD: 07195  Ensembl: ENSG00000169760 
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2 Entrez:23542  HPRD: 09674  Ensembl: ENSG00000008735  HGNC: 6883 
CACNG4calcium channel, voltage-dependent, gamma subunit 4 Entrez:27092  HGNC: 1408  Ensembl: ENSG00000075461  HPRD: 05911 
CACNG2calcium channel, voltage-dependent, gamma subunit 2 Entrez:10369  HGNC: 1406  HPRD: 04220 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CACNG3calcium channel, voltage-dependent, gamma subunit 3
NLGN1neuroligin 1
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2
CACNG4calcium channel, voltage-dependent, gamma subunit 4
CACNG2calcium channel, voltage-dependent, gamma subunit 2
Query geneGeneGene descriptionEdge score
CACNG3CACNG3calcium channel, voltage-dependent, gamma subunit 3
NLGN1NLGN1neuroligin 1
MAPK8IP2MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2
CACNG4CACNG4calcium channel, voltage-dependent, gamma subunit 4
CACNG2CACNG2calcium channel, voltage-dependent, gamma subunit 2

Troyanskaya Laboratory - Princeton University