ASD

GO:0051057 positive regulation of small GTPase mediated signal transduction (26)

GeneInput weightStandardRank
KRAS--157
RELN1.01626
MAP2K10.251907
SHOC2--982
DGKI--1124
RAC1--1617
IGF10.2512793
KITLG--3334
CDON--3487
LPAR1--4170
FGF10--14532
HRAS0.2515086
ITPKB--6178
ALS2--16326
LPAR2--6450
CSF1--6542
NOTCH2--16664
ABRA--7831
RASGRP4--8409
GPR55--8693
NRAS--114119
ARRB1--19906
F2RL1--19969
F2R--20036
EPO--20282
ERBB2--123130

Network

GO:0051057

Network
Enrichment
NameDescriptionExternal IDs
KRASKirsten rat sarcoma viral oncogene homolog Entrez:3845  Ensembl: ENSG00000133703  HGNC: 6407  HPRD: 01817 
RELNreelin Entrez:5649  HGNC: 9957  Ensembl: ENSG00000189056  HPRD: 02742 
MAP2K1mitogen-activated protein kinase kinase 1 Entrez:5604  HGNC: 6840  HPRD: 01469 
SHOC2soc-2 suppressor of clear homolog (C. elegans) Entrez:8036  Ensembl: ENSG00000108061  HGNC: 15454  HPRD: 04144 
DGKIdiacylglycerol kinase, iota Entrez:9162  HPRD: 07238  HGNC: 2855  Ensembl: ENSG00000157680 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
KRASKirsten rat sarcoma viral oncogene homolog
RELNreelin
MAP2K1mitogen-activated protein kinase kinase 1
SHOC2soc-2 suppressor of clear homolog (C. elegans)
DGKIdiacylglycerol kinase, iota
Query geneGeneGene descriptionEdge score
KRASKRASKirsten rat sarcoma viral oncogene homolog
RELNRELNreelin
MAP2K1MAP2K1mitogen-activated protein kinase kinase 1
SHOC2SHOC2soc-2 suppressor of clear homolog (C. elegans)
DGKIDGKIdiacylglycerol kinase, iota

Troyanskaya Laboratory - Princeton University