ASD

GO:0045620 negative regulation of lymphocyte differentiation (26)

GeneInput weightStandardRank
SFRP1--387
SOCS5--463
ID2--2154
RC3H1--2217
BCL6--2550
FLT3--14055
INHA--4765
IFNB1--5250
DTX1--5290
PRDX2--5497
GLI3--16261
BMP4--16499
CTLA4--6866
IHH--17160
TNFSF4--7262
FOXJ1--7628
IFNA2--7694
IFNL1--10151
NFKBID--13229
NRARP--14597
INHBA--16974
SHH--118571
JAK3--20340
IL4R--20610
CD74--24030
ZC3H8--24341

Network

GO:0045620

Network
Enrichment
NameDescriptionExternal IDs
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
SOCS5suppressor of cytokine signaling 5 Entrez:9655  HPRD: 06159  HGNC: 16852  Ensembl: ENSG00000171150 
ID2inhibitor of DNA binding 2, dominant negative helix-loop-helix protein Entrez:3398  HPRD: 02664  HGNC: 5361  Ensembl: ENSG00000115738 
RC3H1ring finger and CCCH-type domains 1 Entrez:149041  Ensembl: ENSG00000135870  HPRD: 13913  HGNC: 29434 
BCL6B-cell CLL/lymphoma 6 Entrez:604  HGNC: 1001  Ensembl: ENSG00000113916  HPRD: 00180 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SFRP1secreted frizzled-related protein 1
SOCS5suppressor of cytokine signaling 5
ID2inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
RC3H1ring finger and CCCH-type domains 1
BCL6B-cell CLL/lymphoma 6
Query geneGeneGene descriptionEdge score
SFRP1SFRP1secreted frizzled-related protein 1
SOCS5SOCS5suppressor of cytokine signaling 5
ID2ID2inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
RC3H1RC3H1ring finger and CCCH-type domains 1
BCL6BCL6B-cell CLL/lymphoma 6

Troyanskaya Laboratory - Princeton University