ASD

GO:0032147 activation of protein kinase activity (148)

GeneInput weightStandardRank
KRAS--157
GAP43--60
ADNP1.0171
YWHAB0.251107
ADCY2--175
GRM50.251240
ADCY10.251466
DGKZ--547
PRKACB--584
KIDINS220--701
TGFB2--834
MAP2K10.251907
NRG10.251936
ADORA1--960
GRM10.251975
CALCA--1013
DGKI--1124
MAPK1--1128
MAP3K5--1220
MAP2K20.2511240
PRKAR1B--1257
CHRNA3--1266
MAP3K7--1275
DGKB--1341
PRLR0.2511393
ADRA2A0.2511399
TNIK--1531
TAOK20.2511633
ACVR2B--11676
PDPK1--1740
ZFP91--1788
PARD3--1845
ADCY9--1850
CCK0.2511899
SPECC1L--1912
CARTPT0.2511957
DGKG--2155
PRKAR2B--2211
PRKAR1A--12428
MAPKBP1--2654
CRK--2713
ADCY8--2785
MAP3K13--2864
ADCY6--2877
PTK2B--3063
RAF10.2513236
WNT5A--3319
MAP3K1--13381
CCDC88A--3536
DGKE--3651
MAP3K4--3663
DRD20.2513749
DLG1--3822
EDNRA--13857
FLT10.2513953
PRKACG--4112
ANGPT1--4182
ADCY5--4295
AXIN1--14419
DGKD--4786
HRAS0.2515086
SPHK2--5120
CERK--5270
ADCY3--5755
GNAI2--5860
INSR--15872
NGF0.2516229
STRADA--6362
MAPK30.2516426
BMP4--16499
PDGFC--6530
DGKH--6642
TNFSF15--6782
CHRM1--6796
PLCE1--6929
HTR2B--6992
FRS2--7173
TAB1--7218
TGFBR1--17268
PILRB--7462
PRKD3--7603
IL2--7838
RAPGEF1--7926
HTR1B0.2518092
GADD45B--8312
ADORA2A0.2518408
NTRK10.2518522
ADRA2C--8551
LAMTOR2--8770
LRRK2--18802
ADCY4--9091
KISS1R--9434
EDN1--9540
PRKACA--9630
DGKQ--9874
GHR--110098
ADRA2B--10119
TGFBR2--110407
TLR6--10981
TRAF6--11055
BRAF--111149
PICK1--11315
PRKAR2A--11450
HCRT0.25111633
ITGB30.5111817
EGF0.25112881
MAP3K11--12938
GADD45G--13071
RAP1A--13091
MS4A2--13136
FGF2--13150
MALT1--13522
TNFRSF10B--13570
NRAS--114119
CARD14--14340
CERKL--114754
TNF0.25115243
DGKK--16992
BDKRB1--18217
PSEN1--18523
EDN2--18677
AZU1--18895
JAK2--119561
F2R--20036
PDGFB--21071
CLSPN--21302
TRAF7--21319
AGK--21412
IRAK1--21640
TNFRSF10A--21740
INS--122047
LRP1--22276
MAP4K1--22336
TLR3--22478
DGKA--23016
ADRB20.25123251
STRADB--23510
IKBKG--123539
SLC11A1--23561
TRAF2--23686
CARD10--23869
SPHK1--24069
ANG--124879
CDK1--25053
ADAM9--125221
PPAP2A--25298
ADCY7--25408
TPX2--25683

Network

GO:0032147

Network
Enrichment
NameDescriptionExternal IDs
KRASKirsten rat sarcoma viral oncogene homolog Entrez:3845  Ensembl: ENSG00000133703  HGNC: 6407  HPRD: 01817 
GAP43growth associated protein 43 Entrez:2596  Ensembl: ENSG00000172020  HPRD: 01198  HGNC: 4140 
ADNPactivity-dependent neuroprotector homeobox Entrez:23394  Ensembl: ENSG00000101126  HPRD: 09793  HGNC: 15766 
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Entrez:7529  HGNC: 12849  Ensembl: ENSG00000166913  HPRD: 03184 
ADCY2adenylate cyclase 2 (brain) Entrez:108  HGNC: 233  HPRD: 00052  Ensembl: ENSG00000078295 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
KRASKirsten rat sarcoma viral oncogene homolog
GAP43growth associated protein 43
ADNPactivity-dependent neuroprotector homeobox
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
ADCY2adenylate cyclase 2 (brain)
Query geneGeneGene descriptionEdge score
KRASKRASKirsten rat sarcoma viral oncogene homolog
GAP43GAP43growth associated protein 43
ADNPADNPactivity-dependent neuroprotector homeobox
YWHABYWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
ADCY2ADCY2adenylate cyclase 2 (brain)

Troyanskaya Laboratory - Princeton University