ASD

GO:0051493 regulation of cytoskeleton organization (196)

GeneInput weightStandardRank
MAPT0.25176
MAP2--106
APC0.251266
EP300--1318
MAPRE1--331
STMN2--343
CLASP2--375
SFRP1--387
MAP1B--403
RICTOR--537
PFN1--548
PFN2--551
CDK5R1--586
SLIT2--659
SNCA--1667
TAC10.251726
CLIP3--730
NEBL--731
TSC10.251790
ACTR3--803
SMAD3--823
ARPC1A--901
SHROOM2--937
PARK20.251952
CLASP1--955
RNF4--973
PROX1--997
DST--1092
XPO1--1095
KANK1--1150
CDKN1B--1162
DLC1--1282
SPTAN1--11287
AMOT--1325
TAOK1--1336
BAIAP20.2511353
DMTN--1465
RAC1--1617
SPTBN4--1647
ARPC2--1648
VANGL2--1793
ARHGEF2--1819
ARPC5L--1833
SPTBN2--11935
RASA1--1983
TMSB10--2139
SSH2--2172
CAPZB--2179
MARK2--2280
RHOA--2292
ADD2--2388
ARPC5--2454
STMN3--2468
LATS1--2781
PLXNB1--2853
ADD1--12876
ARPC4--2880
TMSB15A--2947
FZD10--2957
NCK2--3077
TMSB15B--3139
ARF6--3317
MAP3K1--13381
SPTB--3478
CCDC88A--3536
SPTBN1--3627
INPP5J--3690
PDGFA--3731
DIXDC1--3734
ACTR3B--3786
NEB--3801
DLG1--3822
CAPN6--3996
SSH1--4066
CLIP1--4193
LIMK1--4265
S1PR1--4301
CAPZA2--4483
JAM3--4580
CYLD--14624
RDX--14697
WNT3A--4747
TERF1--4825
PAK1--4940
DYNLT1--4976
CAPZA1--4983
MLST8--5028
TMEM67--15217
SPTBN5--5319
ARHGAP6--5374
ARPC1B--5545
TBCD--5702
JMY--5725
ARL2--5930
NF2--15991
CELSR1--6180
TMSB4X--6302
DSTN--6316
ARPC3--6500
SPTA1--16958
ARHGEF10--7111
ILK--7305
GRHL3--7409
CRIPAK--7596
CXCL12--7802
WNT11--7820
P2RX7--7888
AVIL--7943
CAPZA3--8396
DYNC1LI1--8558
KATNB1--8593
CTNNB10.519066
MID1IP1--9080
STMN1--9278
KISS1R--9434
CAMSAP3--9445
EDN1--9540
CCL11--9615
SCIN--9620
CEP76--9743
CDC42EP5--9805
WASH3P--10817
WASH2P--11022
TWF1--11060
TACR1--11618
RHOC--11655
MYLK3--12362
SORBS3--12437
PDXP--12453
ESPN--112835
NCK1--12890
TMSB4Y--13524
WASH6P--13829
TRIM54--13879
TMSB4XP8--14081
RHOQ--14092
NES--14479
ARHGEF19--14560
PRKCQ--15381
CAV3--115414
WASH1--15718
TRPV4--115988
HDAC6--16779
TMSB4XP4--17717
WASH4P--17760
ARHGEF10L--17881
CDC42EP2--19500
F2RL1--19969
MAP4--20072
ACTR3C--20146
CORO1A--20339
CAPG--20663
MAP6D1--20928
MTOR--21095
CDK5RAP2--121330
SBDS--21769
CCL21--21829
NPM1--121865
CCL24--21868
CLIC4--22003
VIL10.5122243
LRP1--22276
VILL--22283
SKA2--22319
CCR7--22367
GPR65--22555
NEXN--122655
CCL26--22814
TWF2--23010
SDC4--23067
PDGFRB--23242
NCKAP1L--23771
FKBP4--23829
SSH3--23947
CEP250--23960
GSN--124007
BAIAP2L1--24041
TRIOBP--124113
PLEK--24240
TPM1--124247
LIMA1--24553
SKA1--24562
BRCA1--124573
SKA3--24589
PSRC1--24652
FHOD1--24802
BORA--24836
ARAP1--24899
SYNPO--25125
RANBP1--25143
CCNB1--25174
CHORDC1--25294
PLK4--25369
CAV1--125381
CCNF--25571
TPX2--25683

Network

GO:0051493

Network
Enrichment
NameDescriptionExternal IDs
MAPTmicrotubule-associated protein tau Entrez:4137  HGNC: 6893  Ensembl: ENSG00000186868  HPRD: 01142 
MAP2microtubule-associated protein 2 Entrez:4133  HPRD: 01140  HGNC: 6839  Ensembl: ENSG00000078018 
APCadenomatous polyposis coli Entrez:324  HGNC: 583  HPRD: 01439  Ensembl: ENSG00000134982 
EP300E1A binding protein p300 Entrez:2033  Ensembl: ENSG00000100393  HGNC: 3373  HPRD: 04078 
MAPRE1microtubule-associated protein, RP/EB family, member 1 Entrez:22919  HGNC: 6890  HPRD: 04379  Ensembl: ENSG00000101367 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MAPTmicrotubule-associated protein tau
MAP2microtubule-associated protein 2
APCadenomatous polyposis coli
EP300E1A binding protein p300
MAPRE1microtubule-associated protein, RP/EB family, member 1
Query geneGeneGene descriptionEdge score
MAPTMAPTmicrotubule-associated protein tau
MAP2MAP2microtubule-associated protein 2
APCAPCadenomatous polyposis coli
EP300EP300E1A binding protein p300
MAPRE1MAPRE1microtubule-associated protein, RP/EB family, member 1

Troyanskaya Laboratory - Princeton University