ASD

GO:0032321 positive regulation of Rho GTPase activity (55)

GeneInput weightStandardRank
RASGRF1--335
SFRP1--387
GSK3B--427
ARHGAP5--464
JUN--511
TSC10.251790
SOS1--1810
ARHGAP35--908
NDEL10.2511074
DLC1--1282
THY1--1580
DOCK40.2511765
PREX1--2760
FZD10--2957
PTK2B--3063
PREX2--3163
ARHGAP1--3304
CDKL5--13600
ARHGAP26--13662
ARHGAP29--4559
ARAP3--4767
MYO9B0.515005
ARHGAP6--5374
RHOG--6279
ALS2--16326
OPHN10.516584
RALBP1--6643
ERRFI1--6649
GRHL3--7409
SYDE2--7604
FOXJ1--7628
PIN1--7940
CCL11--9615
SYDE1--9690
ARHGAP8--11916
ARHGEF19--14560
CCL19--14578
TAX1BP3--15553
ARHGEF10L--17881
EPHA2--119467
CDC42EP2--19500
DOCK7--19597
ARHGAP15--21045
ARHGEF16--21200
ARHGAP4--21362
CCL21--21829
CCL24--21868
GMIP--22274
CCR7--22367
GPR65--22555
CCL26--22814
SCRIB--23676
NCKAP1L--23771
ARHGAP27--23975
ARAP1--24899

Network

GO:0032321

Network
Enrichment
NameDescriptionExternal IDs
RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1 Entrez:5923  HGNC: 9875  Ensembl: ENSG00000058335 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
GSK3Bglycogen synthase kinase 3 beta Entrez:2932  Ensembl: ENSG00000082701  HPRD: 05418  HGNC: 4617 
ARHGAP5Rho GTPase activating protein 5 Entrez:394  HPRD: 04060  HGNC: 675  Ensembl: ENSG00000100852 
JUNjun proto-oncogene Entrez:3725  HGNC: 6204  HPRD: 01302  Ensembl: ENSG00000177606 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1
SFRP1secreted frizzled-related protein 1
GSK3Bglycogen synthase kinase 3 beta
ARHGAP5Rho GTPase activating protein 5
JUNjun proto-oncogene
Query geneGeneGene descriptionEdge score
RASGRF1RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1
SFRP1SFRP1secreted frizzled-related protein 1
GSK3BGSK3Bglycogen synthase kinase 3 beta
ARHGAP5ARHGAP5Rho GTPase activating protein 5
JUNJUNjun proto-oncogene

Troyanskaya Laboratory - Princeton University