ASD

GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter (9)

GeneInput weightStandardRank
RBPJ--1595
SREBF2--2312
SCAP--2683
SRF--2841
NOTCH1--12865
RBM15--4247
NKX2-50.2518486
ARHGEF10L--17881
SREBF1--19464

Network

GO:0010552

Network
Enrichment
NameDescriptionExternal IDs
RBPJrecombination signal binding protein for immunoglobulin kappa J region Entrez:3516  Ensembl: ENSG00000168214  HGNC: 5724  HPRD: 00920 
SREBF2sterol regulatory element binding transcription factor 2 Entrez:6721  HGNC: 11290  HPRD: 02726  Ensembl: ENSG00000198911 
SCAPSREBF chaperone Entrez:22937  HPRD: 03300  HGNC: 30634  Ensembl: ENSG00000114650 
SRFserum response factor (c-fos serum response element-binding transcription factor) Entrez:6722  HGNC: 11291  Ensembl: ENSG00000112658  HPRD: 02788 
NOTCH1notch 1 Entrez:4851  HPRD: 01827  HGNC: 7881  Ensembl: ENSG00000148400 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
RBPJrecombination signal binding protein for immunoglobulin kappa J region
SREBF2sterol regulatory element binding transcription factor 2
SCAPSREBF chaperone
SRFserum response factor (c-fos serum response element-binding transcription factor)
NOTCH1notch 1
Query geneGeneGene descriptionEdge score
RBPJRBPJrecombination signal binding protein for immunoglobulin kappa J region
SREBF2SREBF2sterol regulatory element binding transcription factor 2
SCAPSCAPSREBF chaperone
SRFSRFserum response factor (c-fos serum response element-binding transcription factor)
NOTCH1NOTCH1notch 1

Troyanskaya Laboratory - Princeton University