ASD

GO:0048048 embryonic eye morphogenesis (26)

GeneInput weightStandardRank
SOX11--96
LRP6--279
RARB0.251300
HIPK1--311
SP3--562
PAX2--653
PROX1--997
HIPK2--1051
BMP7--1137
TFAP2A--12923
WNT5A--3319
VAX2--3553
WNT16--4117
SP1--4195
AXIN1--14419
TH0.2514933
TWIST1--16980
IHH--17160
FRS2--7173
FOXL2--17521
KDM2B--8359
RARG0.2518575
LRP5--19420
CRYAA--10509
STRA6--110685
ALDH1A3--21739

Network

GO:0048048

Network
Enrichment
NameDescriptionExternal IDs
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
RARBretinoic acid receptor, beta Entrez:5915  HPRD: 07183  Ensembl: ENSG00000077092  HGNC: 9865 
HIPK1homeodomain interacting protein kinase 1 Entrez:204851  HGNC: 19006  Ensembl: ENSG00000163349  HPRD: 06418 
SP3Sp3 transcription factor Entrez:6670  HPRD: 03483  HGNC: 11208  Ensembl: ENSG00000172845 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX11SRY (sex determining region Y)-box 11
LRP6low density lipoprotein receptor-related protein 6
RARBretinoic acid receptor, beta
HIPK1homeodomain interacting protein kinase 1
SP3Sp3 transcription factor
Query geneGeneGene descriptionEdge score
SOX11SOX11SRY (sex determining region Y)-box 11
LRP6LRP6low density lipoprotein receptor-related protein 6
RARBRARBretinoic acid receptor, beta
HIPK1HIPK1homeodomain interacting protein kinase 1
SP3SP3Sp3 transcription factor

Troyanskaya Laboratory - Princeton University