ASD

GO:0032925 regulation of activin receptor signaling pathway (13)

GeneInput weightStandardRank
ACVR1B--510
ACVR2A--965
SMAD7--1192
FKBP1A--1284
ACVR2B--11676
LEMD3--12084
SKI--2904
FGF10--14532
MEN1--14917
ACVR1--16054
FST--14783
INHBA--16974
FSTL3--25154

Network

GO:0032925

Network
Enrichment
NameDescriptionExternal IDs
ACVR1Bactivin A receptor, type IB Entrez:91  Ensembl: ENSG00000135503  HGNC: 172  HPRD: 03193 
ACVR2Aactivin A receptor, type IIA Entrez:92  HGNC: 173  HPRD: 00025  Ensembl: ENSG00000121989 
SMAD7SMAD family member 7 Entrez:4092  HPRD: 04241  HGNC: 6773  Ensembl: ENSG00000101665 
FKBP1AFK506 binding protein 1A, 12kDa Entrez:2280  Ensembl: ENSG00000088832  HGNC: 3711  HPRD: 01741 
ACVR2Bactivin A receptor, type IIB Entrez:93  HGNC: 174  HPRD: 04106 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ACVR1Bactivin A receptor, type IB
ACVR2Aactivin A receptor, type IIA
SMAD7SMAD family member 7
FKBP1AFK506 binding protein 1A, 12kDa
ACVR2Bactivin A receptor, type IIB
Query geneGeneGene descriptionEdge score
ACVR1BACVR1Bactivin A receptor, type IB
ACVR2AACVR2Aactivin A receptor, type IIA
SMAD7SMAD7SMAD family member 7
FKBP1AFKBP1AFK506 binding protein 1A, 12kDa
ACVR2BACVR2Bactivin A receptor, type IIB

Troyanskaya Laboratory - Princeton University